Related Experiment Video

Updated: Nov 22, 2025

Surgical Placement of Catheters for Long-term Cardiovascular Exercise Testing in Swine
12:37

Surgical Placement of Catheters for Long-term Cardiovascular Exercise Testing in Swine

Published on: February 9, 2016

13.7K

Blood pressure variability in patients with angina and non-obstructive coronary artery disease

Ahmed Alaarag1, Osama Amin2

  • 1Department of Cardiology, Tanta University, Tanta, Egypt. a_f_elarag@yahoo.com.

Journal of Human Hypertension
|January 8, 2021
PubMed

Insights

Blood pressure variability (BPV) is linked to angina severity in patients with non-obstructive coronary artery disease. Diastolic BPV parameters, including average real variability (ARV) and standard deviation (SD), independently predict angina severity.

Area of Science:

  • Cardiology
  • Hypertension Research

Background:

  • Management of ischemia with non-obstructive coronary artery disease presents challenges.
  • Persistent angina in these patients requires further mechanistic investigation.
  • Blood pressure variability (BPV) is a potential contributing factor to angina.

Purpose of the Study:

  • To investigate the relationship between BPV and angina severity in patients with non-obstructive coronary artery disease.
  • To identify specific BPV parameters associated with anginal symptoms.

Main Methods:

  • Study included 150 patients with chest pain and evidence of myocardial ischemia but non-obstructive coronary arteries.
  • Ambulatory blood pressure monitoring was used to assess BPV.
  • Statistical analysis, including correlation and regression, was performed.

Main Results:

  • A positive correlation was found between BPV (measured by ARV and SD) and angina severity (p<0.001).
  • Diastolic BPV parameters (24H, day, night ARV and SD) were identified as independent predictors of angina severity (p<0.05).

Conclusions:

  • Short-term BPV, specifically ARV and SD, is consistently associated with angina in patients with non-obstructive coronary artery disease.
  • Diastolic BPV parameters are significant independent predictors of angina severity in this population.

More Related Videos

Ultrasound Assessment of Endothelial-Dependent Flow-Mediated Vasodilation of the Brachial Artery in Clinical Research08:42

Ultrasound Assessment of Endothelial-Dependent Flow-Mediated Vasodilation of the Brachial Artery in Clinical Research

Published on: October 22, 2014

27.7K
Oxygenation-sensitive Cardiac MRI with Vasoactive Breathing Maneuvers for the Non-invasive Assessment of Coronary Microvascular Dysfunction08:35

Oxygenation-sensitive Cardiac MRI with Vasoactive Breathing Maneuvers for the Non-invasive Assessment of Coronary Microvascular Dysfunction

Published on: August 17, 2022

2.8K

Related Concept Videos

Special considerations while measuring blood pressure01:28

Special considerations while measuring blood pressure

When assessing blood pressure (BP), healthcare professionals must consider various factors and potential unexpected outcomes to ensure accurate readings and provide proper patient care. Adhering to these guidelines is essential to achieving the most reliable results.
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
977
Measurement of Blood Pressure01:17

Measurement of Blood Pressure

Assessing blood pressure is a standard procedure executed in virtually all medical environments. The method utilized today was established over a hundred years ago by an innovative Russian doctor, Dr. Nikolai Korotkoff. The soft ticking noise, known as Korotkoff sounds, heard while taking blood pressure readings results from turbulent blood flow within the vessels. The apparatus required for this procedure includes a sphygmomanometer, a blood pressure cuff attached to a gauge, and a...
2.2K
Angina II: Classification01:27

Angina II: Classification

Angina, also known as angina pectoris, is a chest pain resulting from diminished blood flow to the heart muscle and is often a symptom of coronary artery disease. Angina presents several variants with distinctive attributes, etiologies, and therapeutic approaches. The main types of angina include stable, unstable, variant (Prinzmetal's), microvascular, intractable, and silent ischemia.Stable angina is caused by atherosclerosis, which leads to the formation of plaques that narrow the coronary...
117
Angina III: Clinical Manifestations and Assessment01:29

Angina III: Clinical Manifestations and Assessment

Angina manifests as chest pain, tightness, or squeezing discomfort typically located behind the breastbone. It can radiate to the neck, jaw, shoulders, and inner aspects of the upper arms, most commonly the left arm. Patients may experience shortness of breath, fatigue, profuse sweating, dizziness, indigestion, heartburn, palpitations, anxiety, and vomiting as accompanying symptoms. This pain often lasts a few minutes and is triggered by physical exertion, emotional stress, heavy meals, or cold...
92
Assessment of blood pressure in brachial artery(two-step method)01:23

Assessment of blood pressure in brachial artery(two-step method)

Measuring blood pressure is a fundamental skill in healthcare that aids in diagnosing and monitoring hypertension and other cardiovascular conditions. An aneroid sphygmomanometer, commonly used in clinical settings, offers a manual and precise method for blood pressure measurement. The technique for using this instrument involves specific steps that must be carefully executed to ensure accuracy. The following detailed description outlines a two-step technique for assessing blood pressure using...
1.2K
Hypertension and Regulation of Blood Pressure01:18

Hypertension and Regulation of Blood Pressure

Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
3.5K