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HoBi-Like Pestivirus and Reproductive Disorders
1Department of Veterinary Medicine, University of Bari Aldo Moro, Valenzano, Italy.
Frontiers in Veterinary Science
|January 8, 2021
Summary
HoBi-like pestivirus (HoBiPeV) significantly impacts cattle reproduction, causing economic losses. Further research is needed for better diagnostics and understanding vaccine cross-protection against this emerging bovine pathogen.
Area of Science:
- Veterinary Virology
- Ruminant Infectious Diseases
- Reproductive Pathology
Background:
- HoBi-like pestivirus (HoBiPeV) is an emerging pestivirus found globally in cattle and other ruminants.
- HoBiPeV infections can lead to diverse clinical presentations, from asymptomatic cases to severe disease, causing significant economic losses in cattle production.
- Reproductive failure is a major consequence of HoBiPeV infections in cattle.
Purpose of the Study:
- To review the current literature on the impact of HoBiPeV infection on cattle reproduction.
- To consolidate information on reproductive disorders associated with HoBiPeV in cattle.
- To highlight knowledge gaps in diagnostics and vaccine efficacy.
Main Methods:
- Literature review of scientific articles and experimental data.
- Analysis of reported reproductive disorders in naturally and experimentally infected cattle.
- Inclusion of available in-vitro studies on HoBiPeV and the reproductive tract.
Main Results:
- HoBiPeV is identified as a significant bovine pathogen affecting reproduction.
- Various reproductive disorders have been documented in cattle infected with HoBiPeV.
- Limited in-vitro data exists regarding HoBiPeV's direct effects on reproductive tissues.
Conclusions:
- HoBiPeV must be recognized as a key bovine pathogen impacting reproductive health.
- There is a critical need for developing more specific and sensitive diagnostic tools for HoBiPeV.
- The extent of cross-protection offered by existing bovine viral diarrhea virus (BVDV) vaccines against HoBiPeV requires further investigation.
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