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Updated: Jun 16, 2026

Longitudinal In Vivo Imaging of the Cerebrovasculature: Relevance to CNS Diseases

Longitudinal In Vivo Imaging of the Cerebrovasculature: Relevance to CNS Diseases

Published on: December 6, 2016

Cerebral Small Vessel Disease.

Jakub Litak^1,2, Marek Mazurek¹, Bartłomiej Kulesza¹

¹Department of Neurosurgery and Pediatric Neurosurgery, Medical University of Lublin, 20-954 Lublin, Poland.

International Journal of Molecular Sciences

|January 9, 2021

Summary

This summary is machine-generated.

Cerebral small vessel disease (CSVD) involves various vascular disorders affecting the brain

Keywords:

CMB CSVD cerebral microbleeds cerebral small vessel disease

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Longitudinal In Vivo Imaging of the Cerebrovasculature: Relevance to CNS Diseases

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A Volumetric Method for Quantification of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage

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Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions

Published on: April 23, 2021

Area of Science:

Neurology
Vascular Biology
Pathology

Background:

Cerebral small vessel disease (CSVD) encompasses diverse vascular disorders impacting the brain's intricate vasculature.
Oxidative stress is a key pathological mechanism in CSVD, leading to epithelial cell degeneration.
Classifications include Binswanger's disease, leukoaraiosis, cerebral microbleeds (CMBs), and lacunar strokes.

Purpose of the Study:

To characterize cerebral small vessel disease (CSVD).
To review the impact of current knowledge on CSVD diagnosis and treatment.

Main Methods:

Literature review of CSVD characteristics.
Analysis of current diagnostic and therapeutic strategies for CSVD.

Main Results:

CSVD affects small arteries, capillaries, arterioles, and venules.
Oxidation processes contribute significantly to CSVD pathology.
Understanding CSVD aids in patient diagnosis and management.

Conclusions:

CSVD is a complex group of diseases with oxidative stress as a central mechanism.
Current knowledge enhances the diagnosis and treatment of patients with CSVD.
Further research into CSVD pathophysiology can improve patient outcomes.