Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Role of Vitamins in Maintaining Bone Health01:25

Role of Vitamins in Maintaining Bone Health

4.5K
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
4.5K
Essential Minerals for Bone Health01:31

Essential Minerals for Bone Health

5.5K
The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
5.5K
The Functions of the Skeletal System01:22

The Functions of the Skeletal System

5.3K
The most apparent functions of the skeletal system are support, protection, and movement. However, bone tissue also performs several other critical metabolic functions. For one, the bone matrix acts as a reservoir for a number of minerals important to the functioning of the body, especially calcium and phosphorus. These minerals, present in the bone tissue, can be released back into the bloodstream when required. Calcium ions, for example, are essential for muscle contractions and controlling...
5.3K
Bone Disorders01:29

Bone Disorders

4.9K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
4.9K
What is the Skeletal System?01:02

What is the Skeletal System?

55.5K
Overview
55.5K
Hormones and Bone Tissue01:17

Hormones and Bone Tissue

3.4K
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
3.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparison of Fracture Risk Following Semaglutide Treatment vs Sleeve Gastrectomy.

AACE endocrinology and diabetes·2025
Same author

High prevalence of laboratory abnormalities indicative of secondary osteoporosis detected by systematic testing.

JBMR plus·2025
Same author

<i>CDC73</i> c.1155-3A>G is a pathogenic variant that causes aberrant splicing, disrupted parafibromin expression, and hyperparathyroidism-jaw tumor syndrome.

JBMR plus·2024
Same author

Regional citrate anticoagulation with continuous renal replacement therapy as a cause of hypercalcemia.

Archives of osteoporosis·2024
Same author

Hypercalcemia Associated with Pregnancy and Lactation.

Endocrinology and metabolism clinics of North America·2024
Same author

Proceedings of the 2023 Santa Fe Bone Symposium: Progress and Controversies in the Management of Patients with Skeletal Diseases.

Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry·2023

Related Experiment Video

Updated: Nov 22, 2025

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
07:56

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts

Published on: January 29, 2018

18.0K

Nutritional Supplements and Skeletal Health.

Laila S Tabatabai1, Deborah E Sellmeyer2

  • 1Division of Endocrinology, Houston Methodist Hospital, Houston, TX, USA.

Current Osteoporosis Reports
|January 9, 2021
PubMed
Summary
This summary is machine-generated.

Calcium and vitamin D supplements reduce fracture risk in those with low intakes. More research is needed on other nutrient supplements for bone health and fracture prevention.

Keywords:
Bone densityFractureNutritionOsteoporosis

More Related Videos

Using Real-Time Cell Metabolic Flux Analyzer to Monitor Osteoblast Bioenergetics
09:43

Using Real-Time Cell Metabolic Flux Analyzer to Monitor Osteoblast Bioenergetics

Published on: March 1, 2022

3.5K
Evaluation of Amino Acid Consumption in Cultured Bone Cells and Isolated Bone Shafts
06:32

Evaluation of Amino Acid Consumption in Cultured Bone Cells and Isolated Bone Shafts

Published on: April 13, 2022

1.9K

Related Experiment Videos

Last Updated: Nov 22, 2025

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
07:56

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts

Published on: January 29, 2018

18.0K
Using Real-Time Cell Metabolic Flux Analyzer to Monitor Osteoblast Bioenergetics
09:43

Using Real-Time Cell Metabolic Flux Analyzer to Monitor Osteoblast Bioenergetics

Published on: March 1, 2022

3.5K
Evaluation of Amino Acid Consumption in Cultured Bone Cells and Isolated Bone Shafts
06:32

Evaluation of Amino Acid Consumption in Cultured Bone Cells and Isolated Bone Shafts

Published on: April 13, 2022

1.9K

Area of Science:

  • Nutritional science
  • Bone biology
  • Gerontology

Background:

  • Nutrition is crucial for skeletal health across the lifespan.
  • Limited data exist on nutritional supplements' effects on bone density and fracture risk.

Purpose of the Study:

  • To review current literature on nutritional supplements and bone health.
  • Focus on human studies and nutrients with available bone density or fracture data.

Main Methods:

  • Literature review of human studies.
  • Emphasis on nutrients with available bone density or fracture data.

Main Results:

  • Calcium and vitamin D supplements reduce fracture risk, especially in low-intake populations.
  • Isoflavones show potential for improving bone density, but fracture data are lacking.
  • Effect sizes for nutrient interventions are small, necessitating large sample sizes.

Conclusions:

  • Calcium and vitamin D are effective for fracture risk reduction.
  • Further research is needed to clarify the role of other nutrient supplements.
  • Nutrition is a lifelong, population-wide intervention for skeletal health.