Related Experiment Video
Updated: Nov 22, 2025
05:31
Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
Published on: August 7, 2017
10.7K
Bidirectional association between asthma and otitis media in children
So Young Kim1, Hye-Rim Kim2, Chanyang Min3,4
1Department of Otorhinolaryngology-Head & Neck Surgery, CHA Bundang Medical Center, CHA University, Seongnam, Korea.
Summary
Asthma and otitis media (middle ear infection) are linked in children. Children with asthma are more likely to develop otitis media, and those with otitis media have an increased risk of asthma.
Area of Science:
- Pediatric Medicine
- Epidemiology
- Respiratory Health
Background:
- Otitis media and asthma are common childhood conditions.
- The relationship between these two conditions requires further investigation.
Purpose of the Study:
- To explore the bidirectional association between otitis media and asthma in children.
- To determine if a history of asthma increases the risk of developing otitis media.
- To determine if a history of otitis media increases the risk of developing asthma.
Main Methods:
- Utilized the Korean Health Insurance Review and Assessment Service-National Sample Cohort (2002-2013).
- Study I: 14,665 asthma patients (aged <15) were matched with controls to assess otitis media incidence.
- Study II: 27,043 otitis media patients were matched with controls to assess asthma incidence.
- Stratified Cox proportional hazard models analyzed hazard ratios (HRs).
Main Results:
- Asthma patients showed a significantly higher HR for developing otitis media (HR=1.46, P<0.001).
- Otitis media patients demonstrated a significantly higher HR for developing asthma (HR=1.43, P<0.001).
Conclusions:
- Asthma and otitis media exhibit a significant bidirectional relationship in pediatric populations.
- Findings suggest a potential common etiology or shared risk factors contributing to both conditions.
Related Concept Videos
01:29Asthma-I: Introduction
3.0K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
3.0K
01:26Asthma-II: Pathophysiology and Classification
3.6K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
3.6K
01:20Asthma: Pathogenesis and Management
978
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
978
01:30Asthma-IV: Diagnostic and Management
2.8K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
2.8K
01:24Asthma-III: Symptoms and Complications
2.9K
Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Classification of Asthma
2.9K
01:25Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs
1.5K
Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
1.5K