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Bidirectional association between asthma and otitis media in children

So Young Kim1, Hye-Rim Kim2, Chanyang Min3,4

  • 1Department of Otorhinolaryngology-Head & Neck Surgery, CHA Bundang Medical Center, CHA University, Seongnam, Korea.

Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology
|January 10, 2021
PubMed

Insights

Asthma and otitis media (middle ear infection) are linked in children. Children with asthma are more likely to develop otitis media, and those with otitis media have an increased risk of asthma.

Area of Science:

  • Pediatric Medicine
  • Epidemiology
  • Respiratory Health

Background:

  • Otitis media and asthma are common childhood conditions.
  • The relationship between these two conditions requires further investigation.

Purpose of the Study:

  • To explore the bidirectional association between otitis media and asthma in children.
  • To determine if a history of asthma increases the risk of developing otitis media.
  • To determine if a history of otitis media increases the risk of developing asthma.

Main Methods:

  • Utilized the Korean Health Insurance Review and Assessment Service-National Sample Cohort (2002-2013).
  • Study I: 14,665 asthma patients (aged <15) were matched with controls to assess otitis media incidence.
  • Study II: 27,043 otitis media patients were matched with controls to assess asthma incidence.
  • Stratified Cox proportional hazard models analyzed hazard ratios (HRs).

Main Results:

  • Asthma patients showed a significantly higher HR for developing otitis media (HR=1.46, P<0.001).
  • Otitis media patients demonstrated a significantly higher HR for developing asthma (HR=1.43, P<0.001).

Conclusions:

  • Asthma and otitis media exhibit a significant bidirectional relationship in pediatric populations.
  • Findings suggest a potential common etiology or shared risk factors contributing to both conditions.
Abstract

Keywords:
AsthmaCohort studiesEpidemiologyOtitis media

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