Related Experiment Video
Updated: Nov 22, 2025

Imaging of the Microstructural Failure Mechanism in the Human Hip
Published on: September 29, 2023
On challenges in clinical assessment of hip fracture risk using image-based biomechanical modelling: a critical
Yunhua Luo1,2
1Department of Mechanical Engineering, University of Manitoba, 75A Chancellor's Circle, Winnipeg, MB, R3T 2N2, Canada. Yunhua.Luo@umanitoba.ca.
Introduction:
Hip fracture is a common health risk among elderly people, due to the prevalence of osteoporosis and accidental fall in the population. Accurate assessment of fracture risk is a crucial step for clinicians to consider patient-by-patient optimal treatments for effective prevention of fractures. Image-based biomechanical modeling has shown promising progress in assessment of fracture risk, and there is still a great possibility for improvement. The purpose of this paper is to identify key issues that need be addressed to improve image-based biomechanical modeling.
Materials And Methods:
We critically examined issues in consideration and determination of the four biomechanical variables, i.e., risk of fall, fall-induced impact force, bone geometry and bone material quality, which are essential for prediction of hip fracture risk. We closely inspected: limitations introduced by assumptions that are adopted in existing models; deficiencies in methods for construction of biomechanical models, especially for determination of bone material properties from bone images; problems caused by separate use of the variables in clinical study of hip fracture risk; availability of clinical information that are required for validation of biomechanical models.
Results And Conclusions:
A number of critical issues and gaps were identified. Strategies for effectively addressing the issues were discussed.

