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Related Concept Videos

Glaucoma: Overview01:25

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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Open Angle Glaucoma: Treatment01:27

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
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Related Experiment Video

Updated: Nov 22, 2025

Conjunctival Commensal Isolation and Identification in Mice
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Ocular Microbiota and Intraocular Inflammation.

Jing Jing Li1, Sanjun Yi1, Lai Wei1

  • 1State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.

Frontiers in Immunology
|January 11, 2021
PubMed
Summary
This summary is machine-generated.

The ocular microbiota, or microbes in the eye, plays a crucial role in eye health. An imbalance in these microbes can lead to inflammatory eye diseases.

Keywords:
eyeintraocular inflammationocular inflammatory diseaseocular microbiotaocular surface microbiome

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Area of Science:

  • Ophthalmology
  • Microbiology
  • Immunology

Background:

  • The ocular surface harbors a diverse community of microorganisms known as the ocular microbiota.
  • Commensal microbes are vital for regulating host metabolism, immune system development, and defense against pathogens.
  • Dysbiosis of the ocular microbiota can precipitate pathogenic overgrowth, leading to inflammation.

Conclusions:

  • The ocular microbiota is integral to maintaining eye health.
  • Understanding the role of microbial dysbiosis is key to addressing inflammatory eye diseases.
  • Modulating the ocular microbiota offers promising therapeutic potential for treating intraocular inflammation.