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Analyzing Protein Architectures and Protein-Ligand Complexes by Integrative Structural Mass Spectrometry
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Advances in integrative structural biology: Towards understanding protein complexes in their cellular context

Samantha J Ziegler1, Sam J B Mallinson1, Peter C St John1

  • 1Biosciences Center, National Renewable Energy Laboratory, 15013 Denver West Parkway, Golden, CO 80401, USA.

Computational and Structural Biotechnology Journal
|January 11, 2021
PubMed

Keywords:
CLEM, correlated light and electron microscopyCrosslinking mass spectrometryCryo-electron microscopyCryo-electron tomographyEPR, electron paramagnetic resonanceFRET, Forster resonance energy transferISB, Integrative structural biologyIntegrative structural biologyML, machine learningMR, molecular replacementMSAs, multiple sequence alignmentsMX, macromolecular crystallographyNMR, nuclear magnetic resonancePDB, Protein Data BankProtein dockingProtein structure predictionQuinary interactionsSAD, single-wavelength anomalous dispersionSANS, small angle neutron scatteringSAXS, small angle X-ray scatteringX-ray crystallographyXL-MS, cross-linking mass spectrometrycryo-EM SPA, cryo-EM single particle analysiscryo-EM, cryo-electron microscopycryo-ET, cryo-electron tomography

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