Related Experiment Video
Updated: Nov 22, 2025

06:13
Endoscopic Septoplasty with Limited Two-line Resection: Minimally Invasive Surgery for Septal Deviation
Published on: June 20, 2018
17.4K
No Opioids after Septorhinoplasty: A Multimodal Analgesic Protocol.
Bradley R Hall1, Katherine L Billue2, Heidi Hon2
1Department of Surgery, University of Nebraska Medical Center, Omaha, Nebr.
Plastic and Reconstructive Surgery. Global Open
|January 11, 2021
Summary
A new multimodal pain management protocol significantly reduced opioid prescriptions after septorhinoplasty. This approach safely eliminated the need for opioids in 76% of patients, benefiting public health.
Area of Science:
- Otolaryngology
- Pain Management
- Public Health
Background:
- Nasal surgeries, including septorhinoplasty, contribute to unused opioid prescriptions.
- Reducing opioid reliance post-surgery is crucial for public health and patient well-being.
Purpose of the Study:
- To evaluate the effectiveness of a 15-component multimodal analgesic protocol in eliminating opioid use after septorhinoplasty.
- To assess the impact of the protocol on patient outcomes, pain scores, and satisfaction.
Main Methods:
- A 15-component multimodal analgesic protocol was implemented for 42 patients undergoing septorhinoplasty.
- Data collected included patient demographics, surgical details, protocol compliance, opioid requirements, pain scores, and satisfaction.
Main Results:
- 76% of patients did not require opioid prescriptions post-discharge.
- Opioid use was inversely correlated with protocol compliance (P = 0.007).
- Patients requiring opioids had higher pain scores postoperatively but equivalent satisfaction.
Conclusions:
- The multimodal protocol safely omitted opioid prescriptions in the majority of septorhinoplasty patients.
- This approach demonstrates a viable strategy to reduce opioid consumption in this patient population without compromising outcomes.
More Related Videos
Related Concept Videos
Opioid Analgesics: Synthetic and Semisynthetic Opioids
665
Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...
665
Analgesia and Pain Management
1.2K
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
1.2K
Opioid Analgesics: Morphine and Other Natural Cogeners
595
Opioids are a class of drugs that mimic endogenous opioid peptides and act on opioid receptors, and help in pain relief. These compounds are classified as natural, synthetic, or semi-synthetic. Natural opioids, like morphine, codeine, and thebaine, are derived from the opium poppy plant (Papaver somniferum or Papaver album) and are termed opiates. Synthetic opioids are artificial, while semi-synthetic opioids combine natural and synthetic compounds. Morphine, a prototypical opioid, possesses a...
595
Epistaxis
367
Epistaxis, or nosebleeds, occurs when small, swollen blood vessels in the nasal mucous membrane rupture. Typically, the anterior septum is the primary site of occurrence.
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
367
Parenteral Anesthetics: Overview
425
Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.
425

