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Secondary ocular malignancies: A review.
Aaron M Yeung1, Jill R Wells1, Hans E Grossniklaus1
1Ocular Oncology & Ophthalmic Pathology, Emory Eye Center, Atlanta, Georgia, USA.
Clinical & Experimental Ophthalmology
|January 11, 2021
Summary
Ocular metastases, often spreading to the choroid, now have a better prognosis due to advancements like immunotherapy. Early diagnosis and treatment by ophthalmologists are crucial for preserving vision and coordinating care with oncologists.
Area of Science:
- Ophthalmology
- Oncology
- Medical Research
Background:
- Secondary ocular malignancies frequently metastasize to the choroid.
- Historically, the prognosis for choroidal metastases was poor.
- Advances in systemic cancer treatment have improved patient life expectancy.
Purpose of the Study:
- To highlight the importance of timely diagnosis of secondary ocular malignancies.
- To emphasize the role of ophthalmologists in managing ocular involvement.
- To underscore the need for multidisciplinary collaboration between ophthalmology and oncology.
Main Methods:
- Review of current literature on ocular metastases.
- Analysis of treatment outcomes with newer therapies.
- Discussion of diagnostic and management strategies.
Main Results:
- Improved patient survival rates due to systemic therapies and immunotherapy.
- Potential for vision preservation with prompt ocular treatment.
- Necessity for integrated care pathways.
Conclusions:
- Ophthalmologists play a critical role in the early detection and management of choroidal metastases.
- Multidisciplinary care is essential for optimizing both visual outcomes and systemic cancer treatment.
- Timely intervention can significantly improve the quality of life for patients with secondary ocular malignancies.
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