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Related Concept Videos

Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

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Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
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Mitral Regurgitation III: Medical Management01:25

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Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Related Experiment Video

Updated: Nov 22, 2025

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
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Is surgery the fair competitor for MitraClip?

Michele Di Mauro1, Eliana Raviola2, Stefano Guarracini3

  • 1Cardio-Thoracic Surgery Department, Heart and Vascular Centre, Maastricht University Medical Centre (MUMC), Cardiovascular Research Institute Maastricht (CARIM), Maastricht, The Netherlands.

Journal of Cardiac Surgery
|January 11, 2021
PubMed
Summary

Surgery remains the gold standard for mitral regurgitation (MR). The MitraClip device is not a surgical competitor but may suit high-risk primary MR patients.

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Area of Science:

  • Cardiovascular Medicine
  • Interventional Cardiology
  • Cardiac Surgery

Background:

  • The intervention overlap between cardiac surgeons and interventional cardiologists is increasing, particularly for heart valve disease.
  • While aortic valve interventions face competition, mitral regurgitation treatment options are evolving.
  • The role of MitraClip versus traditional surgery for mitral regurgitation requires clarification.

Purpose of the Study:

  • To evaluate if surgical intervention is a viable competitor to MitraClip for mitral regurgitation.
  • To analyze current evidence comparing surgical outcomes with MitraClip therapy.

Main Methods:

  • A meta-analysis of 11 observational studies and 1 randomized trial was conducted.
  • Evidence regarding surgical intervention and MitraClip for mitral regurgitation was summarized.

Main Results:

  • The meta-analysis concluded that surgery is not a direct competitor to MitraClip.
  • Recent trials (MITRA-FR, COAPT) used medical therapy, not surgery, as the comparator for MitraClip.

Conclusions:

  • For mitral regurgitation (MR), surgery remains the established gold standard treatment.
  • MitraClip is a suitable option for primary MR in patients with high surgical risk.
  • The efficacy of MitraClip for secondary MR, especially with impaired left ventricular function, requires further investigation.