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Fasciculation frequency is a questionable biomarker for motor unit loss in amyotrophic lateral sclerosis

Josef Finsterer1, Fulvio A Scorza2

  • 1Klinik Landstrasse, Messerli Institute, Vienna, Austria.

Brain Communications
|January 11, 2021
PubMed
Abstract

No abstract available in PubMed .

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The contraction strength of muscles is regulated by motor neurons, which modulate the frequency of action potentials dispatched to the motor units based on the body's requirements. This process of varying the muscle stimulation frequency allows muscles to contract with a force that is precisely tailored to the needs of the moment, whether lifting a feather or a heavy box.
Wave summation
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