Related Experiment Video

Updated: Nov 22, 2025

Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach
04:53

Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach

Published on: October 18, 2024

1.1K

Impact of obstructive sleep apnea on assisted ventilation in children with asthma exacerbation

Po-Yang Tsou1,2, Christopher Cielo2,3, Melissa S Xanthopoulos3

  • 1Department of Pediatrics, Driscoll Children's Hospital, Corpus Christi, Texas, USA.

Pediatric Pulmonology
|January 11, 2021
PubMed

Insights

Obstructive sleep apnea (OSA) significantly increases the risk of severe asthma exacerbations in children, leading to greater need for mechanical ventilation, longer hospital stays, and higher costs.

Area of Science:

  • Pediatric Pulmonology
  • Sleep Medicine
  • Health Services Research

Background:

  • Asthma exacerbations are a common cause of pediatric hospitalization.
  • Obstructive sleep apnea (OSA) is an increasingly recognized comorbidity in children.
  • The impact of OSA on asthma exacerbation severity in pediatric populations requires further investigation.

Purpose of the Study:

  • To determine the association between obstructive sleep apnea (OSA) and the severity of asthma exacerbations in hospitalized children.
  • To evaluate the impact of OSA on the need for mechanical ventilation, length of hospital stay, and hospitalization costs.

Main Methods:

  • Retrospective cohort study utilizing the Kids' Inpatient Database (2000-2012).
  • Inclusion criteria: children aged 2-18 years admitted for acute asthma exacerbation.
  • Statistical analysis included multivariable logistic, negative binomial, and linear regression to assess the impact of OSA on outcomes.

Main Results:

  • Obstructive sleep apnea (OSA) was identified in 0.75% of pediatric asthma hospitalizations.
  • OSA was significantly associated with increased odds of invasive mechanical ventilation (IMV) and noninvasive mechanical ventilation (NIMV).
  • Children with OSA experienced longer lengths of hospital stay (LOS) and higher inflation-adjusted hospitalization costs.

Conclusions:

  • Obstructive sleep apnea (OSA) is an independent risk factor for increased severity and resource utilization in pediatric asthma exacerbations.
  • OSA is linked to greater need for mechanical ventilation, prolonged hospital stays, and elevated healthcare costs.
  • These findings highlight the importance of screening for OSA in children with severe asthma exacerbations.
Abstract

Keywords:
asthmachildrenmechanical ventilationobstructive sleep apnea

More Related Videos

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea07:54

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

20.2K
Laryngeal Mask Airway LMA Placement in a Neonatal Patient Simulator Using a Non-Inflatable Supraglottic Airway SGA04:56

Laryngeal Mask Airway LMA Placement in a Neonatal Patient Simulator Using a Non-Inflatable Supraglottic Airway SGA

Published on: July 14, 2023

4.0K

Related Concept Videos

Sleep Apnea01:21

Sleep Apnea

Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
312
Factors Affecting Pulmonary Ventilation01:19

Factors Affecting Pulmonary Ventilation

Besides the pressure difference between the external environment and the lungs, the airflow rate and ease of pulmonary ventilation are also influenced by three other factors: surface tension of the fluid in the alveoli, compliance of the lungs, and airway resistance.
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
2.3K
Cardiopulmonary Resuscitation II: ACLS Airway Management01:22

Cardiopulmonary Resuscitation II: ACLS Airway Management

Airway management is a key skill in emergency and critical care settings, as maintaining a clear airway is essential for adequate oxygenation and ventilation.Head Tilt-Chin Lift TechniqueThe head tilt-chin lift maneuver is an essential technique primarily used in patients without suspected cervical spine injuries. To perform this maneuver, one hand is placed on the patient’s forehead, and gentle pressure is applied backward to tilt the head. The fingertips of the other hand are positioned...
312
Mechanical Ventilation III: Noninvasive Ventilation01:23

Mechanical Ventilation III: Noninvasive Ventilation

Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
Noninvasive Positive-Pressure Ventilation...
363
Respiratory Assessment: Purpose and Indications01:19

Respiratory Assessment: Purpose and Indications

Respiratory assessment is a cornerstone of nursing assessments, crucial for the early detection of patient deterioration. This evaluation transcends routine procedures, representing a critical skill nurses must master to ensure optimal patient care.
Objectives and Importance:
The primary goal of respiratory assessment is to evaluate patients at early risk of clinical deterioration. Since respiratory distress often precedes other signs of declining health, breathing patterns and sounds become a...
1.4K
Assessment of Airway, Skin Color, and Use of Accessory Muscles01:30

Assessment of Airway, Skin Color, and Use of Accessory Muscles

A thorough assessment of respiratory health is paramount in clinical settings to identify and manage respiratory distress and ensure adequate oxygenation. This article elaborates on the critical aspects of respiratory evaluation, including airway assessment, skin color examination, and the observation of accessory muscle use, which are integral to effectively diagnosing and managing patients with respiratory conditions.
Introduction
The initial evaluation of a patient's respiratory system...
1.3K