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Persistent Complete Heart Block in a Patient with COVID-19 Infection: a Case Report

Zahra Hosseini1, Saeed Ghodsi1,2, Seyed Fakhreddin Hejazi1

  • 1Department of Cardiology, Shahid Beheshti Hospital, Qom University of Medical Sciences, Qom, Iran.

SN Comprehensive Clinical Medicine
|January 12, 2021
PubMed

Insights

COVID-19 can cause advanced atrioventricular block (AVB), a serious heart condition. This case study highlights a persistent AVB in a COVID-19 patient, emphasizing the need for monitoring and potential intervention.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Internal Medicine

Background:

  • The COVID-19 pandemic necessitates understanding its diverse clinical manifestations, especially cardiovascular complications.
  • Advanced atrioventricular block (AVB) is an uncommon but serious cardiac complication of COVID-19, with limited reported incidence.
  • The pathophysiology linking COVID-19 infection to AVB remains incompletely understood.

Purpose of the Study:

  • To report a case of advanced atrioventricular block (AVB) in a patient with COVID-19.
  • To highlight the persistence of AVB following COVID-19 recovery.
  • To discuss potential pathophysiological mechanisms and management strategies for COVID-19-associated AVB.

Main Methods:

  • Case report of a 48-year-old male with COVID-19 infection.
  • Clinical presentation, diagnostic confirmation (PCR, pulmonary involvement), and electrocardiographic findings of complete AVB.
  • Follow-up assessment of cardiac conduction post-recovery.

Main Results:

  • The patient presented with symptoms for 5 days prior to diagnosis of complete AVB.
  • COVID-19 diagnosis was confirmed with PCR and evidence of pulmonary involvement.
  • The atrioventricular block persisted for over one month after the patient's recovery from COVID-19.

Conclusions:

  • COVID-19 infection can lead to advanced atrioventricular block (AVB).
  • Potential contributing factors include inflammatory response, immune dysregulation, myocarditis, and medications.
  • While conservative management may suffice, pacemaker implantation is a consideration for persistent conduction defects.

Keywords:
Atrioventricular blockCOVID-19InfectionInflammationPacemakerSARS-CoV-2

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