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Cancer Statistics, 2021.

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Summary
This summary is machine-generated.

Cancer death rates are declining due to reduced smoking and better treatments, with lung cancer showing significant progress. Despite this, momentum has slowed for other common cancers, highlighting the need for continued research and intervention.

Keywords:
cancer casescancer statisticsdeath ratesincidencemortality

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Area of Science:

  • Oncology
  • Public Health
  • Cancer Epidemiology

Background:

  • The American Cancer Society provides annual estimates of cancer incidence and mortality in the U.S.
  • Cancer death rates have declined since 1991, attributed to reduced smoking and improved detection/treatment.
  • This decline represents 3.2 million fewer deaths than if peak rates had continued.

Purpose of the Study:

  • To present the latest U.S. cancer statistics for 2021.
  • To analyze trends in cancer incidence and mortality.
  • To evaluate the impact of interventions on cancer death rates.

Main Methods:

  • Utilized data from the Surveillance, Epidemiology, and End Results (SEER) Program, National Program of Cancer Registries (NPCR), and North American Association of Central Cancer Registries (NAACCR) for incidence (through 2017).
  • Employed mortality data from the National Center for Health Statistics (NCHS) (through 2018).
  • Calculated annual percentage changes in mortality rates for specific cancer types and overall.

Main Results:

  • Projected 1,898,160 new cancer cases and 608,570 deaths in the U.S. for 2021.
  • Overall cancer death rate declined 31% from its 1991 peak through 2018.
  • Lung cancer mortality decline accelerated, accounting for nearly half of the total mortality reduction from 2014-2018, with improved survival for non-small cell lung cancer (NSCLC).

Conclusions:

  • Accelerated progress against lung cancer, driven by improved treatments, has led to a record drop in overall cancer mortality.
  • While lung cancer mortality declines have accelerated, progress has slowed for prostate, breast, and colorectal cancers.
  • Continued advancements in early detection and treatment are crucial for further reducing cancer burden.