Related Experiment Video
Updated: Nov 21, 2025

Large-Scale SARS-CoV-2 Testing Utilizing Saliva and Transposition Sample Pooling
Published on: June 23, 2022
A minimal model for household-based testing and tracing in epidemics
Greg Huber1, Mason Kamb1, Kyle Kawagoe2
1Chan Zuckerberg Biohub, San Francisco, CA 94158, United States of America.
Abstract:
In a previous work (Huberet al.2020Phys. Biol.17065010), we discussed virus transmission dynamics modified by a uniform clustering of contacts in the population: close contacts within households and more distant contacts between households. In this paper, we discuss testing and tracing in such a stratified population. We propose a minimal tracing strategy consisting of random testing of the entire population plus full testing of the households of those persons found positive. We provide estimates of testing frequency for this strategy to work.
Related Concept Videos
Steps in Outbreak Investigation
Principles of Disease Surveillance
Statistical Methods for Analyzing Epidemiological Data
Introduction to Epidemiology
Mechanistic Models: Compartment Models in Individual and Population Analysis
Statistical Software for Data Analysis and Clinical Trials

