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Normal thyroid volume in subjects evaluated in a primary ambulatory setting in Liguria
Massimo Giusti1,2, Marilena Sidoti3,4
1Unit of Endocrinology, Centro Diagnostico Priamar, Savona, Italy - omsv1416@gmail.com.
Minerva Endocrinology
|January 13, 2021
Summary
This study establishes normal thyroid volume (TV) reference ranges for the Ligurian population using ultrasonography. These findings provide crucial data for comparing individual thyroid volumes in clinical practice.
Area of Science:
- Endocrinology
- Medical Imaging
- Public Health
Background:
- Ultrasonography (US) is a primary method for assessing thyroid volume (TV).
- Normal TV data for the Ligurian, Italy population were previously unavailable.
- Establishing regional normative data is essential for accurate clinical interpretation.
Purpose of the Study:
- To determine and report normative thyroid volume (TV) reference ranges for the Ligurian population.
- To provide a baseline for comparing individual thyroid volumes in this specific geographic region.
- To investigate factors influencing thyroid volume in the study population.
Main Methods:
- Retrospective analysis of 483 euthyroid subjects from endocrine evaluations in Liguria.
- Inclusion criteria: normal thyroid ultrasound, absence of autoantibodies and interfering medications.
- Thyroid volume (TV) measured via ultrasonography; anthropometric data, smoking, and residence district recorded.
Main Results:
- Median TV was 8.0 mL in females and 11.8 mL in males (P<0.0001).
- Female smokers had larger TV than non-smokers (P=0.01).
- Significant positive correlations observed between TV and weight, height, BMI, and body surface area (BSA) in both sexes.
Conclusions:
- Reference values for thyroid volume (TV) in the Ligurian population are now established.
- These normative data enable comparison with individual thyroid volumes in clinical settings.
- The study highlights variations in TV based on sex, smoking status, and region of residence.
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