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Related Experiment Video

Updated: Nov 21, 2025

Diagnosis of Hirschsprung's Disease by Immunostaining Rectal Suction Biopsies for Calretinin, S100 Protein and Protein Gene Product 9.5
05:45

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A Hirschsprung Pull-through, "with a Twist".

Hira Ahmad1, Devin R Halleran1, Raquel Quintanilla1

  • 1Department of Pediatric Colorectal and Pelvic Reconstructive Surgery, Nationwide Children's Hospital, Columbus, Ohio, United States.

European Journal of Pediatric Surgery Reports
|January 13, 2021
PubMed
Summary
This summary is machine-generated.

Hirschsprung disease, a common childhood neurocristopathy, can lead to post-surgical enterocolitis. This case highlights a rare cause: a twist of the pull-through, requiring specific diagnosis.

Keywords:
Hirschsprung diseasecongenital intestinal obstructionenterocolitispull-through reoperationtwisted pull-through

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Area of Science:

  • Pediatric Surgery
  • Gastroenterology
  • Developmental Biology

Background:

  • Hirschsprung disease is the most common pediatric neurocristopathy, characterized by congenital absence of enteric ganglia.
  • Surgical resection and bowel reconstruction are standard treatments, typically yielding good outcomes.
  • However, some patients experience recurrent enterocolitis and obstructive symptoms post-surgery.

Observation:

  • Diagnostic tools like contrast enema, examination under anesthesia, and rectal biopsy are used to investigate post-surgical obstruction.
  • A rare cause of obstruction, a twist of the pull-through, was identified in a patient.
  • This specific complication can mimic other obstructive symptoms.

Findings:

  • The study presents a case of a twist of the pull-through as a rare cause of obstructive symptoms after Hirschsprung disease surgery.
  • This diagnosis was confirmed through standard diagnostic procedures.
  • The case underscores the importance of considering rare mechanical complications.

Implications:

  • Recognizing a twist of the pull-through is crucial for appropriate management in children with Hirschsprung disease.
  • Early identification can prevent prolonged diagnostic delays and improve patient outcomes.
  • This finding contributes to the understanding of potential long-term complications following Hirschsprung surgery.