Interim value set for the EQ-5D-5L in Iran using the Crosswalk method.

Area of Science:

• Health Economics
• Psychometrics
• Societal Valuations of Health

Background:

• The EuroQol five-dimensional 5 level (EQ-5D-5L) value set is unavailable for the Iranian general population.
• An existing EuroQol five-dimensional 3 level (EQ-5D-3L) value set is available for Iran.

Purpose of the Study:

• To generate an interim EQ-5D-5L value set for Iran.
• To enable health economic analyses using the EQ-5D-5L instrument in Iran.

Main Methods:

• The crosswalk method was employed, mapping EQ-5D-3L responses to EQ-5D-5L states.
• The EQ-5D-3L value set was previously established using the Time Trade-Off (TTO) method.
• Statistical analysis was performed using STATA version 15.

Main Results:

• The interim EQ-5D-5L value set showed mean and median scores of 0.499 and 0.451, respectively.
• The value range for both EQ-5D-3L and the interim EQ-5D-5L was -0.113 to 0.919.
• Fewer 'good health' states (value > 0.8) were observed in the interim EQ-5D-5L set (0.448%) compared to the EQ-5D-3L set (2.47%).

Conclusions:

• An interim EQ-5D-5L value set was successfully generated for the Iranian general public.
• This new value set can be utilized by researchers and policymakers for economic and clinical evaluations in Iran.