Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reluctance Modulation of Structured Magnetorheological Elastomers for Wireless Biomechanical Sensing.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Analytical modeling for suction cup designs for skin-interfaced wearable devices.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Centrifugal microfluidics for rapid target analyte quantification in airborne bioaerosols.

Lab on a chip·2026
Same author

Skin-interfaced microfluidic capsule and portable lab-on-a-disc platform for sweat-based monitoring of prenatal nutrient balance.

Nature biomedical engineering·2026
Same author

Scalable networks of multimodal haptic arrays for plantar sensory substitution.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Hospice admission of cancer patients receiving disease-modifying therapies near the end of life: implications for eligibility criteria.

Tumori·2026
Same journal

Vertically Stacked Indium Gallium Zinc Oxide-Based Three-Dimensional Integrated Circuits.

ACS nano·2026
Same journal

Tunable Nanoparticle Thin-Film Reveals Distance Dependence of Auger-Mediated Radiation Enhancement in Diffuse Midline Glioma.

ACS nano·2026
Same journal

G-Quadruplex Network Engineering in Ionogels: Realizing Robust Biosensing Interfaces for Plant Electrophysiology.

ACS nano·2026
Same journal

Announcing the 2026 <i>ACS Nano</i> Lectureship and <i>ACS Nano</i> Impact Award Laureates.

ACS nano·2026
Same journal

Ultrafast Self-Assembly of Zeolitic Imidazolate Framework-8 Enables Antibody Orientation for Ultrasensitive Lateral Flow Immunoassays.

ACS nano·2026
Same journal

Interfacial Salt Engineering with Alkali and Ammonium Additives for Stable Pure-Blue Perovskite Light-Emitting Diodes and Micropatterned Displays.

ACS nano·2026
See all related articles

Related Experiment Video

Updated: Nov 21, 2025

Continuous-wave Thulium Laser for Heating Cultured Cells to Investigate Cellular Thermal Effects
09:49

Continuous-wave Thulium Laser for Heating Cultured Cells to Investigate Cellular Thermal Effects

Published on: June 30, 2017

8.0K

Bioresorbable Microdroplet Lasers as Injectable Systems for Transient Thermal Sensing and Modulation.

Daniel Franklin1,2, Tyler Ueltschi3, Andrea Carlini2

  • 1Department of Materials Science and Engineering, Northwestern University, Evanston, Illinois 60208, United States.

ACS Nano
|January 13, 2021
PubMed
Summary
This summary is machine-generated.

Researchers developed injectable, bioresorbable microparticle lasers for precise temperature sensing and thermal modulation in living tissues. These functional nanomaterials offer remote sensing and biocompatibility for advanced biological and clinical applications.

Keywords:
biodegradableimagingself-organizationsensorstemperature

More Related Videos

Custom-designed Laser-based Heating Apparatus for Triggered Release of Cisplatin from Thermosensitive Liposomes with Magnetic Resonance Image Guidance
07:47

Custom-designed Laser-based Heating Apparatus for Triggered Release of Cisplatin from Thermosensitive Liposomes with Magnetic Resonance Image Guidance

Published on: December 13, 2015

9.3K
Subsurface Defect Localization by Structured Heating Using Laser Projected Photothermal Thermography
11:34

Subsurface Defect Localization by Structured Heating Using Laser Projected Photothermal Thermography

Published on: May 15, 2017

11.4K

Related Experiment Videos

Last Updated: Nov 21, 2025

Continuous-wave Thulium Laser for Heating Cultured Cells to Investigate Cellular Thermal Effects
09:49

Continuous-wave Thulium Laser for Heating Cultured Cells to Investigate Cellular Thermal Effects

Published on: June 30, 2017

8.0K
Custom-designed Laser-based Heating Apparatus for Triggered Release of Cisplatin from Thermosensitive Liposomes with Magnetic Resonance Image Guidance
07:47

Custom-designed Laser-based Heating Apparatus for Triggered Release of Cisplatin from Thermosensitive Liposomes with Magnetic Resonance Image Guidance

Published on: December 13, 2015

9.3K
Subsurface Defect Localization by Structured Heating Using Laser Projected Photothermal Thermography
11:34

Subsurface Defect Localization by Structured Heating Using Laser Projected Photothermal Thermography

Published on: May 15, 2017

11.4K

Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Optics

Background:

  • Minimally invasive temperature sensing and thermal modulation are crucial for biological research and clinical care.
  • Bioelectronic devices face limitations; functional nanomaterials offer alternatives with remote sensing and injectability.
  • Existing methods lack the integrated sensing and modulation capabilities demonstrated by novel nanomaterials.

Purpose of the Study:

  • To introduce a transient, bioresorbable system for minimally invasive temperature sensing and thermal modulation in living tissues.
  • To demonstrate the functionality of injectable microparticle lasers as both thermal sensors and distributed thermal modulation vehicles.
  • To evaluate the biocompatibility and efficacy of these nanomaterials in biological applications.

Main Methods:

  • Development of injectable slurries of microparticles self-assembled from cholesteric liquid crystals doped with fluorophores.
  • Encapsulation of microparticle lasers in soft hydrogel shells with tunable bioresorption rates.
  • Characterization of particle sensitivity, lasing threshold, size, and photothermal agent functionality.
  • Ex vivo temperature measurements in Casper fish and cytotoxicity evaluations.

Main Results:

  • Demonstrated injectable, bioresorbable microparticle lasers with temperature-sensitive emission wavelengths (>4-300 nm °C⁻¹).
  • Achieved active temperature feedback (ΔT = 1 °C) and potential for remote thermal transport property evaluation.
  • Confirmed biocompatibility through cytotoxicity assays and successful ex vivo temperature measurement in biological tissues with 0.01 °C resolution.

Conclusions:

  • The developed system offers a novel, multifunctional platform for minimally invasive thermal sensing and modulation in biological applications.
  • Injectable, bioresorbable microparticle lasers present a promising alternative to traditional bioelectronic devices.
  • This technology holds potential for advancing remote sensing, targeted therapy, and thermal diagnostics in clinical and research settings.