Fiber Based Approaches as Medicine Delivery Systems.

Area of Science:

• Biomaterials Science
• Nanotechnology
• Pharmaceutical Sciences

Background:

• Effective drug delivery relies on carriers that maximize therapeutic molecule targeting.
• Micro- and nanofibers are emerging as promising drug carriers.
• Key advantages include high surface area, ease of fabrication, mechanical strength, and controlled release.

Purpose of the Study:

• To review recent advancements in using micro- and nanofibers for drug delivery.
• To discuss various fiber fabrication techniques for drug delivery applications.
• To explore the potential of fiber-based systems in research and clinical settings.

Main Methods:

• Review of literature on micro- and nanofiber fabrication for drug delivery.
• Analysis of prevalent fabrication methods: electrospinning, microfluidics, wet spinning, rotary spinning, and self-assembly.
• Discussion of material properties relevant to drug delivery.

Main Results:

• Micro- and nanofibers exhibit favorable characteristics for drug encapsulation and release.
• Diverse fabrication methods allow for tailored fiber structures and drug release profiles.
• Significant potential exists for translating these systems into practical applications.

Conclusions:

• Fiber-based drug delivery systems show great promise for enhanced therapeutic efficacy.
• Continued research and development in fabrication and application are warranted.
• These advanced materials are poised to impact future drug delivery strategies.