Related Experiment Video
Updated: Nov 21, 2025

09:07
Electroconvulsive Seizures in Rats and Fractionation of Their Hippocampi to Examine Seizure-induced Changes in Postsynaptic Density Proteins
Published on: August 15, 2017
12.4K
[Electroconvulsive therapy in a 12-year-old boy with a severe depression]
Tijdschrift Voor Psychiatrie
|January 14, 2021
Summary
Electroconvulsive therapy (ECT) is an uncommon but effective treatment for severe depression in children and adolescents. This case study highlights successful ECT in a 12-year-old boy, demonstrating its long-term efficacy and safety in youth.
Area of Science:
- Child and Adolescent Psychiatry
- Neuroscience
- Psychopharmacology
Background:
- Electroconvulsive therapy (ECT) is rarely used in pediatric populations, potentially due to limited clinician knowledge.
- Severe depression in youth often presents treatment challenges, necessitating exploration of alternative therapeutic options.
Observation:
- A 12-year-old male presented with severe depression unresponsive to standard pharmacotherapy and psychotherapy.
- The patient underwent electroconvulsive therapy (ECT) as a last resort treatment.
Findings:
- ECT treatment resulted in a successful clinical outcome for the patient.
- The positive effects of ECT were sustained over a six-year follow-up period.
- This case contributes to understanding the efficacy and safety of ECT in pediatric populations.
Implications:
- This case underscores the potential of ECT as a viable treatment for treatment-refractory depression in children and adolescents.
- Further research and education are needed to increase the appropriate utilization of ECT in youth psychiatric care.
- The findings support the consideration of ECT in the management of severe pediatric mood disorders.
Related Concept Videos
Electroconvulsive Therapy
403
Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...
403
Epilepsy and Seizures: Overview
900
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
900
Psychosurgery
232
Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
232
Psychosis: Goals of Pharmacotherapy
320
Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
320
Treatment Strategies for Psychological Disorders
438
Treatment approaches for psychological disorders fall into three main categories: psychological, biological, and sociocultural. Each approach targets different aspects of mental health, requiring varying levels of education and training.
Psychological therapies focus on modifying emotions, thoughts, and behaviors through talking, interpreting, listening, rewarding, challenging, and modeling. Clinical psychologists, counselors, and social workers commonly practice psychotherapy. Clinical...
Psychological therapies focus on modifying emotions, thoughts, and behaviors through talking, interpreting, listening, rewarding, challenging, and modeling. Clinical psychologists, counselors, and social workers commonly practice psychotherapy. Clinical...
438

