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Systemic effects of intraocular epinephrine during cataract surgery
1Department of Ophthalmology, UMD-New Jersey Medical School, Newark.
Annals of Ophthalmology
|January 1, 1988
Summary
Intraocular epinephrine during cataract surgery did not significantly affect blood pressure or heart rate in 62 patients. Dilute epinephrine concentrations appear safe for systemic toxicity during extracapsular cataract extraction.
Area of Science:
- Ophthalmology
- Cardiovascular Physiology
Background:
- Intraocular epinephrine is sometimes used during ophthalmic surgery.
- Systemic effects of intraocular epinephrine require careful evaluation.
Purpose of the Study:
- To assess the impact of intraocular epinephrine on systemic blood pressure and heart rate during cataract surgery.
Main Methods:
- Sixty-two patients undergoing cataract surgery received intraocular balanced salt solution with dilute epinephrine (1:1000).
- Systemic blood pressure, heart rate, and electrocardiogram (ECG) were monitored during epinephrine administration.
Main Results:
- No statistically significant changes in blood pressure or heart rate were observed.
- ECG monitoring revealed no adverse changes during the study period.
Conclusions:
- The administration of dilute intraocular epinephrine during extracapsular cataract extraction is associated with minimal risk of systemic toxicity.
- Ophthalmologists can consider using dilute intraocular epinephrine with confidence regarding systemic cardiovascular stability.