Management of Fontan circulation in pregnancy: a multidisciplinary approach to care

Natasha K Wolfe1, Bethany A Sabol2, Jeannie C Kelly2

  • 1Cardiovascular Division, Department of Internal Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO.

Insights

Women with Fontan circulation face unique pregnancy risks. This review analyzes current literature and outlines a multidisciplinary approach for optimal preconception, pregnancy, and postpartum care for these patients.

Area of Science:

  • Cardiology
  • Reproductive Medicine
  • Pediatric Surgery

Background:

  • The Fontan operation, a palliative surgery for single ventricle congenital heart disease, impacts cardiovascular physiology.
  • Over 70,000 individuals worldwide have Fontan circulation, with a growing population of women reaching childbearing age.
  • Increased Fontan population survival necessitates understanding pregnancy-related risks and management.

Purpose of the Study:

  • To review existing literature on pregnancy in women with Fontan circulation.
  • To describe a multidisciplinary approach for managing these pregnancies.
  • To guide clinical care from preconception through postpartum.

Main Methods:

  • Expert review of current literature on Fontan circulation and pregnancy.
  • Analysis of cardiovascular challenges in Fontan patients during gestation.
  • Description of a center's integrated care model.

Main Results:

  • Limited clinical data currently exists for guiding pregnancy management in this population.
  • Fontan circulation presents unique maternal and fetal risks due to altered hemodynamics.
  • A structured, multidisciplinary approach is essential for optimizing outcomes.

Conclusions:

  • Pregnancy in women with Fontan circulation requires specialized, comprehensive care.
  • Further research is needed to establish evidence-based guidelines.
  • Optimizing preconception, antepartum, intrapartum, and postpartum care is critical for maternal and fetal well-being.

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