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Updated: Nov 21, 2025

Glucose-Stimulated Insulin Secretion via Perfusion through the Mice Vasculature with an Intact Pancreas
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Glucose-Stimulated Insulin Secretion via Perfusion through the Mice Vasculature with an Intact Pancreas

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Intraperitoneal insulin administration in pigs: effect on circulating insulin and glucose levels

Ilze Dirnena-Fusini1, Marte Kierulf Åm2,3, Anders Lyngvi Fougner4

  • 1Department Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway ilze.dirnena-fusini@ntnu.no.

BMJ Open Diabetes Research & Care
|January 16, 2021
PubMed
Summary

Intraperitoneal insulin boluses effectively lower glucose levels, with higher doses increasing systemic insulin. Subcutaneous insulin delivery results in significantly higher circulating insulin levels compared to intraperitoneal administration.

Keywords:
animal experimentationblood glucosediabetes mellitusinsulintype 1

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