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Updated: Nov 21, 2025

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
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A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting

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Temporal trends in preterm birth phenotypes by plurality: Black-White disparity over half a century

Deepa Dongarwar1, Danyal Tahseen2, Liye Wang3

  • 1Center of Excellence in Health Equity, Training, and Research, Baylor College of Medicine, Houston, TX, USA. deepa.dongarwar@bcm.edu.

Journal of Perinatology : Official Journal of the California Perinatal Association
|January 16, 2021
PubMed

Insights

Black mothers experienced higher rates of extreme preterm birth compared to White mothers. Preterm birth disproportionately affects Black mothers and multiple pregnancies, necessitating targeted interventions for these vulnerable groups.

Area of Science:

  • Reproductive Health
  • Perinatal Epidemiology
  • Public Health

Background:

  • Preterm birth remains a significant public health concern globally.
  • Racial and ethnic disparities in preterm birth rates are well-documented.
  • Increasing trends in delayed childbearing and multiple pregnancies may influence preterm birth outcomes.

Purpose of the Study:

  • To analyze temporal trends in preterm birth rates stratified by race and plurality.
  • To investigate the association between maternal race, plurality, and different preterm birth phenotypes.
  • To identify vulnerable subgroups requiring targeted interventions.

Main Methods:

  • Utilized temporal trend analyses for preterm birth data from 1971-2018.
  • Employed adjusted logistic regression models to assess associations.
  • Examined data based on race and plurality of pregnancies.

Main Results:

  • Preterm birth categories included extreme preterm (0.7%), very preterm (1.2%), and moderate-to-late preterm (9.3%).
  • Black mothers faced a significantly higher risk of extreme preterm birth (RR: 2.69) compared to White mothers.
  • Preterm birth rates were disproportionately higher in Black mothers and pregnancies with higher plurality.

Conclusions:

  • Preterm birth rates show persistent racial disparities, particularly impacting Black mothers.
  • Pregnancies involving higher plurality are associated with increased preterm birth risk.
  • Targeted interventions are crucial for addressing the needs of Black mothers and multiple pregnancies to reduce preterm birth disparities.
Abstract

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