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Related Concept Videos

Blood Transfusion01:15

Blood Transfusion

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Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
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Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

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Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
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Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

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A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
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Blood Typing01:10

Blood Typing

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Understanding an individual's blood group is a critical component of transfusion medicine. It ensures compatibility in blood transfusions, organ transplants, and even during pregnancy. Determining these blood groups involves the ABO and Rh blood typing systems, utilizing specific antigens and corresponding anti-sera to identify an individual's blood type.
Antigens are protein molecules that reside on the surface of red blood cells (RBCs). The ABO and Rh blood typing systems target...
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Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

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Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
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Tissue Transplantation01:24

Tissue Transplantation

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Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
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The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
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Updated: Nov 21, 2025

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
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London 2017: Lessons learned in transfusion emergency planning.

Fatts Chowdhury1,2, Heidi Doughty2, Nicola Batrick1

  • 1Imperial College Healthcare NHS Trust, London, UK.

Transfusion Medicine (Oxford, England)
|January 16, 2021
PubMed
Summary

Hospital transfusion services faced challenges during major incidents, with sample handling errors and over-ordering impacting efficiency. Post-incident debriefs proved vital for staff support and service improvement.

Keywords:
emergency planningmajor incidentsstresstransfusion teams

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Area of Science:

  • Transfusion Medicine
  • Emergency Preparedness
  • Healthcare Management

Background:

  • Hospitals must prepare for mass casualty incidents (MCIs), but the specific impact on transfusion services is often overlooked.
  • This study examines the transfusion response to four major incidents within a six-month period, including terrorist attacks and the Grenfell Tower fire.

Purpose of the Study:

  • To describe the transfusion response to four major incidents.
  • To identify practical lessons learned for improving transfusion services during mass casualty events.

Main Methods:

  • A retrospective review of four major incidents in 2017.
  • Data sources included patient administration systems, incident documentation, post-incident debriefs, and the Laboratory Information Management System (TelePath).

Main Results:

  • Thirty-four patients were admitted, with 45 blood samples received. Four patients received blood components (red blood cells, fresh frozen plasma, cryoprecipitate).
  • Key issues identified included sample labelling errors and over-ordering of components, leading to wastage.
  • Transfusion staff deployment within the emergency department and effective staff management ensured service continuity.

Conclusions:

  • Transfusion teams responded to multiple incidents with minimal blood demand, highlighting workload challenges in sample handling.
  • Improved situational awareness is crucial for better blood stock management.
  • Laboratory debriefing systems provide valuable feedback for service enhancement, staff training, and support.