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Updated: Nov 21, 2025

Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage
Published on: August 4, 2021
Description of a late miscarriage case at 16 Weeks of Gestation associated with a SARS-CoV-2 infection
Anne-Sophie Michel1, Victoire De Logiviere2, Aurélie Schnuriger3
1Department of Obstetrics and Gynecology, FHU PREMA, Trousseau Hospital, Paris, France; Sorbonne University, Paris, France.
Background:
Data about obstetric complications of maternal infection by SARS-CoV-2 remain sparse.
Case:
A 40-year-old pregnant woman, gravida 3 para 1 with no previous obstetric complications, presented a late miscarriage at 16 weeks of gestation on day 9 of COVID-19 disease. The results of her nasopharyngeal swab for SARS-CoV-2, tested the same day, were negative, but the placenta was infected by SARS-CoV-2 and serology was positive 11 days later. No other obstetric or infectious cause was found to explain this outcome.
Conclusion:
This case strongly suggests that SARS-CoV-2 may lead to a late miscarriage.
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