Low-cost and open-source strategies for chemical separations

Area of Science:

• Chemistry
• Analytical Chemistry
• Laboratory Science

Background:

• A growing trend towards open-access resources in laboratory research.
• Open-source hardware utilizes widely available parts, including 3D-printable components and low-cost microcontrollers.
• Open-source software reduces reliance on expensive commercial licenses and allows for tailored program design.

Purpose of the Study:

• To review the impact of the open-source movement on chemical separations research over the past five years.
• To cover key areas including general laboratory equipment, sample preparation, separations-based analysis, detection, electronic control, and data processing software.
• To discuss current challenges and future opportunities for open-source adoption in chemical separations.

Main Methods:

• Comprehensive literature review focusing on open-source applications in chemical separations.
• Analysis of research trends in hardware, software, and methodology over a five-year period.
• Identification of common themes and innovations in open-source laboratory practices.

Main Results:

• Open-source strategies are increasingly adopted for general lab equipment and sample preparation.
• Innovations in open-source detection strategies and electronic system control are evident.
• Development of open-source software for data processing enhances analytical workflows.
• Significant cost reductions and increased accessibility are key outcomes.

Conclusions:

• The open-source movement offers substantial benefits for chemical separations, including cost-effectiveness and customization.
• Further adoption is encouraged by addressing remaining hurdles in implementation and standardization.
• Future opportunities lie in expanding open-source solutions across all facets of chemical separations research.