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Updated: Nov 21, 2025

Two-dimensional Porcine Intestinal Organoids Reflecting the Physiological Properties of Native Gut
Published on: January 31, 2025
COMPARATIVE MORPHOLOGY OF THE PIG`S RECTUM AND HUMAN`S RECTUM VIA 3D RECONSTRUCTION
Roman О Plakhotnyi1, Іryna V Кerechanyn1, Larysa Ya Fedoniuk2
1PRIVET HIGHER EDUCATIONAL ESTABLISHMENT «KYIV MEDICAL UNIVERSITY», KYIV, UKRAINE.
Objective:
The aim: To define an ability to use pig as biomodel for experimental and clinical studies in order to develop new approaches of treatment of the rectal pathology.
Patients And Methods:
Materials and methods: For the research two groups were used. I group includes 50 humans (27 females and 23 males), II group includes 8 vietnamese pot-bellied pigs. After magneresonance Imaging the 3D reconstruction of rectum was made.
Results:
Results and conclusions: Topography, structure, age and gender peculiarities of pig`s and human`s rectum in comparative aspect are described in this article. With the help of modern methods, namely 3D reconstruction, the structure of the pig`s and human`s rectum was reconstructed. The morphological parameters, such as size of anorectal and rectosigmoid angles, the length of the rectum and its parts, were determinated. The 3D reconstruction demonstrated that size of anorectal and rectosigmoid angles, the length of the pig`s rectum are morphologicaly identical to the same parametres of human`s rectum. Thus, it is proved that pigs can be used as biomodels in experimental and clinical studies for development the new methods of treatment the rectal pathology in humans.

