Related Experiment Video
Updated: Nov 21, 2025

Functional Imaging of Viral Transcription Factories Using 3D Fluorescence Microscopy
Published on: January 18, 2018
Modification of Nuclear Compartments and the 3D Genome in the Course of a Viral Infection
S V Razin1, A A Gavrilov1, O V Iarovaia1
1Institute of Gene Biology Russian Academy of Sciences.
Abstract:
The review addresses the question of how the structural and functional compartmentalization of the cell nucleus and the 3D organization of the cellular genome are modified during the infection of cells with various viruses. Particular attention is paid to the role of the introduced changes in the implementation of the viral strategy to evade the antiviral defense systems and provide conditions for viral replication. The discussion focuses on viruses replicating in the cell nucleus. Cytoplasmic viruses are mentioned in cases when a significant reorganization of the nuclear compartments or the 3D genome structure occurs during an infection with these viruses.
More Related Videos
Related Concept Videos
Size and Structure of Viral Genomes
Viral Recombination
Viral Structure
Retroviruses
Retrovirus Life Cycles
Viral Mutations

