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[Pain perception and nonsuicidal self-injurious behavior].

M S Zinchuk1, A S Avedisova1,2, N I Voinova1

  • 1Scientific and Practical Psychoneurological Center, Moscow, Russia.

Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova
|January 18, 2021
PubMed
Summary
This summary is machine-generated.

Individuals with nonsuicidal self-injurious (NSSI) behavior show altered pain sensitivity. This review examines neuroimaging, genetic, and psychological factors influencing pain perception in NSSI.

Keywords:
borderline personality disordermental disordersnonsuicidal self-injurious behaviorpain

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Area of Science:

  • Neuroscience
  • Psychology
  • Genetics

Background:

  • Nonsuicidal self-injurious (NSSI) behavior is linked to altered pain perception.
  • Understanding pain sensitivity in NSSI is crucial for developing targeted interventions.

Purpose of the Study:

  • To review and critically analyze studies on pain threshold and tolerance in individuals with NSSI behavior.
  • To explore the neurobiological, genetic, and psychological underpinnings of pain sensitivity in NSSI.

Main Methods:

  • Systematic review of existing literature on pain sensitivity in NSSI.
  • Analysis of neuroimaging, genetic, and psychological study data.
  • Discussion of methodological challenges, including animal modeling.

Main Results:

  • Individuals with NSSI exhibit complex alterations in pain sensitivity.
  • Neuroimaging studies reveal differences in pain processing pathways.
  • Genetic factors, psychological variables, and HPA axis dysregulation contribute to altered pain perception.

Conclusions:

  • Pain sensitivity in NSSI is multifactorial, involving biological and psychological components.
  • Further research is needed to refine methodologies and elucidate causal mechanisms.
  • Findings can inform clinical approaches to NSSI management.