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Medical treatment for acute renal colic
Cristina de la Encarnación Castellano1, Àngela Canós Nebot1, Juan Pablo Caballero Romeu2
1Servicio de Urología. Hospital General Universitario de Alicante. Alicante. España.
Archivos Espanoles De Urologia
|January 18, 2021
Summary
Non-steroidal anti-inflammatory drugs (NSAIDs) are the preferred initial treatment for renal colic, offering better pain control and fewer side effects than opioids. Ondansetron is recommended for managing associated nausea and vomiting.
Area of Science:
- Urology
- Emergency Medicine
- Pharmacology
Background:
- Renoureteral colic (CRU) is a common urological emergency with significant morbidity and healthcare costs.
- Current pharmacological treatment for acute CRU lacks a standardized approach.
Purpose of the Study:
- To evaluate the efficacy and safety of various drugs for acute CRU management.
- To propose a practical treatment guideline for CRU.
- To assess fluid therapy and CRU treatment in pregnant women.
Main Methods:
- Literature search on PubMed using MeSH terms: renal colic, treatment, anti-inflammatory drugs, antiemetic drugs, fluid therapy, pregnant.
- Review of clinical trials, meta-analyses, and systematic reviews (2005-2020).
Main Results:
- Non-steroidal anti-inflammatory drugs (NSAIDs) provide superior pain relief compared to opioids, with reduced need for rescue medication and fewer adverse events.
- Fluid therapy did not demonstrate a significant impact on CRU treatment outcomes.
Conclusions:
- Initiate CRU treatment with NSAIDs, reserving opioids for refractory cases.
- Ondansetron is the recommended first-line agent for controlling nausea and vomiting in CRU.
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