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Phthalate Esters in Foods: Sources, Occurrence, and Analytical Methods.
1Author Cao is with Food Research Div., Bureau of Chemical Safety, Food Directorate, Health Canada, 251 Frederick Banting Driveway, AL: 2203D, Ottawa, Ontario, Canada K1A 0K9. Direct inquiries to author Cao (E-mail: Xu-Liang_Cao@hc-sc.gc.ca).
Comprehensive Reviews in Food Science and Food Safety
|January 20, 2021
Summary
Phthalates, used in plastics and personal care products, contaminate food through environmental exposure and packaging. This review examines phthalate levels in foods and analytical methods to assess human exposure risks.
Area of Science:
- Environmental Chemistry
- Food Safety
- Toxicology
Background:
- Phthalates are widely used as plasticizers and solvents in consumer products.
- Environmental contamination and food packaging migration are key sources of phthalate exposure.
- Toxicological studies indicate potential health risks, including carcinogenicity and teratogenicity.
Purpose of the Study:
- To review phthalate levels in various food items.
- To assess phthalate migration from food packaging materials.
- To identify knowledge gaps in phthalate determination methodologies.
Main Methods:
- Review of existing literature on phthalate levels in foods.
- Analysis of studies on phthalate migration from packaging.
- Evaluation of traditional and novel analytical techniques for phthalate detection.
Main Results:
- Phthalates are detected in diverse food products, including bottled water, soft drinks, and infant formula.
- Migration of phthalates from food packaging materials is a significant exposure pathway.
- Various analytical methods exist, but gaps remain in comprehensive detection and quantification.
Conclusions:
- Food is a major route for human phthalate exposure.
- Further research is needed to address knowledge gaps in phthalate levels and analytical methodologies.
- Understanding phthalate contamination is crucial for human exposure assessment and risk management.

