Related Experiment Video
Updated: Nov 20, 2025

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
Published on: March 14, 2017
Paediatric palliative care: why transfuse?
Guillaume Robert1,2,3, Celine Chappe4, Ana Ferreira2
1Palliative Care Centre, University Hospital, Rennes, Bretagne, France guillaume.robert@chu-rennes.fr.
Insights
In pediatric palliative care, prioritize the child
Area of Science:
- Pediatric Oncology
- Palliative Care
- Hematology
Background:
- Palliative care for children with relapsed neuroblastoma often involves blood transfusions.
- Assessing transfusion needs typically relies on biological markers.
Observation:
- An 8-year-old boy with relapsed stage IV neuroblastoma received extensive transfusions (56 red blood cell, 31 platelet units) over 7.5 months.
- Severe exophthalmia prompted a re-evaluation of the transfusion strategy.
- The child experienced 50 hospitalizations during this period.
Findings:
- Transfusion requirements in palliative care can be substantial, comparable to curative strategies.
- The child's perspective and quality of life should be central to transfusion decisions.
Implications:
- Reassessing transfusion indications collegially and regularly is crucial.
- Further study is needed on the ethical, public health, and practical aspects of transfusion practices in pediatric palliative care.
Abstract:
Should indication for transfusion in paediatric palliative care be based on the child's perspective rather than the biological results? An 8-year-old boy presenting a relapse of a stage IV neuroblastoma received regular blood transfusions. A severe exophtalmia led the doctors to question the transfusion strategy. Over 7.5 months, the child received 56 red blood cell units and 31 platelet units. He was hospitalised 50 times. Indication for blood test and transfusion may be regularly and collegially reassessed. Transfusion needs in a palliative strategy can be as high as in a curative strategy. Practices, benefits but also ethical and public health dimensions should be more studied.
More Related Videos
Related Concept Videos
Blood Transfusion and Agglutination
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
Bone Marrow Sampling and Transplants
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
Blood Transfusion
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Pharmacokinetics in Pediatric Patients: Drug Excretion
Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

