Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

BRIDGING COTYLEDON PATHOLOGY AND PERFUSION IN HEALTHY PRIMATE PREGNANCY.

bioRxiv : the preprint server for biology·2026
Same author

Replicable generation of rhesus macaque iPSCs for <i>in vitro</i> modeling of genetic frontotemporal dementia.

bioRxiv : the preprint server for biology·2026
Same author

Targeted nanoparticles for placenta-specific drug delivery in pregnant rhesus macaques.

Theranostics·2025
Same author

CLDN10-driven lineage decision in an amnion and primordial germ cell progenitor at the amnion-epiblast boundary in primates.

Genome biology·2025
Same author

Exogenous estrogen enhances T cell activation in male primates.

Cell reports·2025
Same author

Monocyte chemoattractant Protein-1 (MCP-1) decreases mineralization of the villous stroma in the macaque placenta.

Placenta·2025
Same journal

Hematology and Serum Biochemistry Reference Intervals for Captive-Born Owl Monkeys (Aotus nancymae): Effects of Age and Sex.

Journal of medical primatology·2026
Same journal

Application of Mobile 3D C-Arm Technology for Diagnostic Imaging of Cleft Palate in an Adult Rhesus Macaque (Macaca mulatta).

Journal of medical primatology·2026
Same journal

Current Landscape of Neonatal/Infant HIV Research: Preclinical and Translational Perspectives.

Journal of medical primatology·2026
Same journal

Clinical Management of Helicobacter Infection in Captive Baboons (Papio anubis and Papio hamadryas), and Isolation and Molecular Characterization of Three Novel Helicobacter Species.

Journal of medical primatology·2026
Same journal

Vitamin D Levels in Captive Bonnet Macaques.

Journal of medical primatology·2026
Same journal

Evaluation of a Point-of-Care Viscoelastic Coagulation Monitor (VCM Vet) and Thromboelastography (TEG) in Bonobos (Pan paniscus).

Journal of medical primatology·2026
See all related articles

Related Experiment Video

Updated: Nov 20, 2025

Fish Sperm Assessment Using Software and Cooling Devices
07:57

Fish Sperm Assessment Using Software and Cooling Devices

Published on: July 28, 2018

9.0K

Comparative computer-assisted sperm analysis in non-human primates.

Jenna K Schmidt1, Katherine D Mean1, Brittany M Dusek1

  • 1Wisconsin National Primate Research Center, Madison, WI, USA.

Journal of Medical Primatology
|January 20, 2021
PubMed
Summary
This summary is machine-generated.

Computer-assisted semen analysis (CASA) establishes baseline sperm motility for non-human primates (NHPs). This tool aids in selecting sires for germline editing research, crucial for developing new disease models.

Keywords:
CASAmacaquemarmosetsperm

More Related Videos

Sperm Collection and Computer-Assisted Sperm Analysis in the Teleost Model Japanese Medaka Oryzias latipes
06:49

Sperm Collection and Computer-Assisted Sperm Analysis in the Teleost Model Japanese Medaka Oryzias latipes

Published on: October 6, 2022

4.4K
Phosphopeptide Analysis of Rodent Epididymal Spermatozoa
09:30

Phosphopeptide Analysis of Rodent Epididymal Spermatozoa

Published on: December 30, 2014

13.2K

Related Experiment Videos

Last Updated: Nov 20, 2025

Fish Sperm Assessment Using Software and Cooling Devices
07:57

Fish Sperm Assessment Using Software and Cooling Devices

Published on: July 28, 2018

9.0K
Sperm Collection and Computer-Assisted Sperm Analysis in the Teleost Model Japanese Medaka Oryzias latipes
06:49

Sperm Collection and Computer-Assisted Sperm Analysis in the Teleost Model Japanese Medaka Oryzias latipes

Published on: October 6, 2022

4.4K
Phosphopeptide Analysis of Rodent Epididymal Spermatozoa
09:30

Phosphopeptide Analysis of Rodent Epididymal Spermatozoa

Published on: December 30, 2014

13.2K

Area of Science:

  • Primate reproductive biology
  • Genomic research tools
  • Comparative animal physiology

Background:

  • Genome-editing strategies are advancing human disease modeling using non-human primates (NHPs).
  • Objective semen evaluation is critical for selecting sires for in vitro fertilization and germline editing in NHPs.
  • Establishing standardized methods is essential for reproducible NHP research.

Purpose of the Study:

  • To establish normative sperm kinematic parameters for three NHP species.
  • To evaluate the utility of Computer-Assisted Semen Analysis (CASA) for NHP semen quality assessment.
  • To provide a baseline for NHP reproductive studies utilizing germline editing.

Main Methods:

  • Sperm motility kinematic parameters were analyzed using a Computer-Assisted Semen Analysis (CASA) instrument.
  • Evaluations were conducted on rhesus macaques (Macaca mulatta), cynomolgus macaques (Macaca fascicularis), and common marmosets (Callithrix jacchus).

Main Results:

  • Normative sperm kinematic parameters were successfully established for the studied NHP species.
  • Significant differences in sperm motility parameters were observed between marmosets and macaques.
  • Seasonal variations in rhesus macaque sperm motility were found to be modest and male-dependent.

Conclusions:

  • Computer-Assisted Semen Analysis (CASA) provides a valuable tool for assessing NHP semen quality.
  • The established normative data serve as a baseline for future NHP reproductive research.
  • These findings support the use of CASA in selecting NHP sires for germline editing applications.