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Published on: June 9, 2023
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Primary epithelioid angiosarcoma of the thyroid: A case report
Sara Bravaccini1, Licia Caprara2, Stefania Cortecchia2
1Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy.
Summary
This case report details a rare thyroid angiosarcoma in a 69-year-old woman. Diagnosis was confirmed via immunohistochemistry, highlighting the importance of specific markers for this aggressive tumor.
Area of Science:
- Oncology
- Pathology
Background:
- Thyroid angiosarcoma is an exceptionally rare and aggressive primary malignant neoplasm.
- Early detection and accurate diagnosis are crucial for managing this challenging condition.
Observation:
- A 69-year-old woman presented with a red, sore neck lesion.
- Imaging revealed a heterogeneous mass in the right thyroid lobe.
- Fine needle aspiration suggested atypical vascular proliferation.
Findings:
- Histopathological examination of the right thyroid lobectomy specimen identified a reddish nodule.
- Immunohistochemistry confirmed angiosarcoma with CD31 and ERG positivity.
- Negative expression of thyroglobulin, calcitonin, and TTF-1 ruled out other thyroid malignancies.
Implications:
- This case underscores the diagnostic utility of immunohistochemistry in identifying rare thyroid cancers.
- Accurate diagnosis of thyroid angiosarcoma is essential for appropriate treatment planning and patient management.
