Related Experiment Video
Updated: Jul 12, 2026

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
Published on: June 9, 2023
Inclusion of Thyroid Nodule Location in American College of Radiology TI-RADS Scoring: Impact on System Performance
Sina Jasim1, Sharlene A Teefey2, Thomas J Baranski1
1Department of Internal Medicine, Division of Endocrinology, Metabolism, and Lipid Research, School of Medicine, Washington University in St. Louis, 660 S Euclid Ave, St. Louis, MO 63110.
Abstract:
Emerging data suggest that the location of thyroid nodules influences malignancy risk. The purpose of this study was to explore the impact of including location in American College of Radiology Thyroid Imaging Reporting and Data System (ACR TI-RADS) scoring. Four of five revised scoring algorithms that added 1 or 2 points to higher-risk locations were associated with lowered accuracy due to lower specificity. However, an algorithm that added 1 point to isthmic nodules did not differ significantly from ACR TI-RADS in accuracy; one additional isthmic cancer was diagnosed for each 10.3 additional benign nodules recommended for biopsy.
Related Concept Videos
Radiological Investigation I: X-ray and CT
Radiological Investigation III: Pulmonary Angiogram and PET Scan
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

