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Updated: Nov 20, 2025
12:10
Retzius-Sparing Robot-Assisted Radical Prostatectomy
Published on: May 19, 2022
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Impact of radical prostatectomy on bladder function as demonstrated on urodynamics study-A systematic review
Henry H Yao1,2,3,4, Venetia Hoe1, Robert T Crump4
1Department of Urology, Western Health, Melbourne, Victoria, Australia.
Neurourology and Urodynamics
|January 21, 2021
Summary
Radical prostatectomy (RP) improves bladder outlet obstruction but can cause new or resolve existing detrusor overactivity. Bladder contractility and compliance may worsen after RP.
Area of Science:
- Urology
- Surgical Oncology
- Urodynamics
Background:
- Radical prostatectomy (RP) is a common treatment for prostate cancer.
- Understanding the impact of RP on bladder function is crucial for patient outcomes.
Purpose of the Study:
- To systematically review urodynamics findings before and after RP.
- To assess the effects of RP on bladder outlet obstruction (BOO), detrusor overactivity (DO), bladder contractility, and compliance.
Main Methods:
- Systematic review of studies with pre- and post-RP urodynamics.
- Searched PubMed, Cochrane, and Embase databases.
- Included 20 articles from 304 screened, excluding symptom-based subgroups.
Main Results:
- RP improved BOO in most patients.
- RP showed mixed effects on DO, with some resolution and some de novo cases, but an overall reduced rate.
- Impaired bladder contractility and compliance were reported in some studies post-RP.
Conclusions:
- RP generally improves bladder outlet obstruction.
- RP has complex effects on detrusor overactivity, often leading to a net reduction.
- Potential for impaired bladder contractility and compliance exists after RP.
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