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Updated: Nov 20, 2025

Author Spotlight: Process Development for the Spray-Drying of Probiotic Bacteria and Evaluation of the Product Quality
Published on: April 7, 2023
Development of novel cocrystal-based active food packaging by a Quality by Design approach
Federica Bianchi1, Fabio Fornari2, Nicolò Riboni3
1University of Parma, Department of Chemistry, Life Sciences and Environmental Sustainability, Parco Area delle Scienze 17/A, 43124 Parma, Italy; University of Parma, Interdepartmental Center for Packaging (CIPACK), Parco Area delle Scienze, 43124 Parma, Italy.
Abstract:
A way to reduce food waste is related to the increase of the shelf-life of food as a result of improving the package type. An innovative active food packaging material based on cocrystallization of microbiologically active compounds present in essential oils i.e. carvacrol, thymol and cinnamaldehyde was developed following the Quality by Design principles. The selected active components were used to produce antimicrobial plastic films with solidified active ingredients on their surface characterized by antimicrobial properties against four bacterial strains involved in fruit and vegetable spoilage. The developed packaging prototypes exhibited good antimicrobial activity in vitro providing inhibition percentage of 69 (±15)% by contact and inhibition diameters of 32 (±6) mm in the gas phase, along with a prolonged release of the active components. Finally, the prolonged shelf-life of grape samples up to 7 days at room temperature was demonstrated.
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