Related Experiment Video
Updated: Nov 20, 2025
05:51
An In Vitro Model for Studying Tau Aggregation Using Lentiviral-mediated Transduction of Human Neurons
Published on: May 23, 2019
6.2K
A rat model expressing a human amyloidogenic kappa light chain
Maria Victoria Ayala1,2, Sébastien Bender1,2, Ignacio Anegon3
1CNRS UMR7276/INSERM U1262, University of Limoges, Limoges, France.
Summary
No abstract available in PubMed .
Related Concept Videos
03:03Amyloid Fibrils
11.2K
Amyloid fibrils are aggregates of misfolded proteins. Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils.
Amyloid deposits were observed as early as 1639 in the liver and the spleen. In 1854, Rudolph Virchow performed iodine staining,...
Amyloid deposits were observed as early as 1639 in the liver and the spleen. In 1854, Rudolph Virchow performed iodine staining,...
11.2K
03:03Amyloid Fibrils
6.1K
6.1K