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Versatile CO2 Transformations into Complex Products: A One-pot Two-step Strategy
Published on: November 9, 2019
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Tris(pentafluorophenyl)borane catalyzed C-C and C-heteroatom bond formation
Gautam Kumar1, Sourav Roy1, Indranil Chatterjee1
1Department of Chemistry, Indian Institute of Technology Ropar, Nangal Road, Rupnagar, Punjab-140001, India. indranil.chatterjee@iitrpr.ac.in.
Organic & Biomolecular Chemistry
|January 22, 2021
Summary
Tris(pentafluorophenyl)borane (BCF) is a versatile Lewis acid catalyst driving metal-free organic synthesis. This review highlights recent BCF-catalyzed transformations for C-C and C-heteroatom bond formation since 2018.
Area of Science:
- Organic Chemistry
- Catalysis
- Materials Science
Background:
- Boron-based Lewis acids are crucial in catalysis.
- Tris(pentafluorophenyl)borane (BCF) is a prominent Lewis acid due to its stability and availability.
- BCF catalysis has seen significant exploration in the last two decades.
Purpose of the Study:
- To review recent advancements in BCF-mediated metal-free catalysis.
- To consolidate knowledge on BCF's role in organic transformations.
- To focus on literature published from 2018 onwards.
Main Methods:
- Literature review of BCF catalysis.
- Categorization of reactions based on bond formation (C-C and C-heteroatom).
- Analysis of BCF's catalytic activity in various organic reactions.
Main Results:
- BCF is effective in promoting diverse metal-free catalytic reactions.
- Significant progress in C-C and C-heteroatom bond formation using BCF.
- Emerging catalytic reactivities of BCF are under continuous investigation.
Conclusions:
- BCF is a powerful tool for sustainable, metal-free synthesis.
- The scope of BCF catalysis continues to expand.
- Recent studies underscore BCF's importance in modern organic chemistry.
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