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Author Spotlight: An Economic and Efficient Method for Quantitative Evaluation of Bone Microarchitecture in a Murine Osteoporosis Model
Published on: September 8, 2023
Osteoporosis in older adults
Béatrice Bouvard1, Cédric Annweiler2, Erick Legrand1
1Service de Rhumatologie, CHU Angers, 4, rue Larrey, 49933 Angers, France; Groupe d'étude sur le remodelage osseux et les biomatériaux, CHU Angers, 4, rue Larrey, 49933 Angers, France; Faculté de Santé, Université d'Angers, Angers, France.
Osteoporosis and fragility fractures are increasing in older adults, leading to higher mortality and re-fracture risks. Despite available treatments, a significant care gap persists, especially for institutionalized elderly patients.
Area of Science:
- Gerontology
- Orthopedics
- Public Health
Background:
- Fragility fracture incidence rises with age, particularly after 50.
- Population aging exacerbates osteoporosis and fracture prevalence globally.
- Older adults face severe consequences from fractures, including increased mortality and secondary fracture risk.
Purpose of the Study:
- To highlight the growing problem of osteoporosis and fragility fractures in aging populations.
- To emphasize the critical role of falls in fracture occurrence among the elderly.
- To underscore the significant treatment gap in osteoporosis management for older adults, especially those in institutions.
Main Methods:
- Review of epidemiological data on aging populations and fracture incidence.
- Analysis of factors contributing to fragility fractures, including bone mineral density and falls.
- Assessment of current osteoporosis diagnosis, fracture risk assessment, and treatment strategies.
Main Results:
- Fragility fractures and their severe consequences (mortality, re-fracture) are strongly age-dependent.
- Falls are a major contributor to fractures in the elderly, necessitating risk assessment.
- A substantial therapeutic care gap exists for osteoporosis treatment in the elderly, particularly in institutional settings.
Conclusions:
- Aging populations face escalating risks of osteoporosis and debilitating fragility fractures.
- Effective fracture risk assessment must incorporate fall risk evaluation.
- Urgent interventions are needed to bridge the treatment gap and improve osteoporosis care for the elderly, especially institutionalized individuals.
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