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Nutrition-based interventions for mood disorders.

Lais B Martins1,2, Jenneffer Rayane Braga Tibães2,3, Marsal Sanches1

  • 1Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center, Houston, Texas, United States.

Expert Review of Neurotherapeutics
|January 25, 2021
PubMed
Summary
This summary is machine-generated.

Nutritional psychiatry shows promise for preventing and treating mood disorders. Dietary patterns and gut health significantly impact mental well-being, with healthy diets reducing risk.

Keywords:
Nutritionbipolar disorderdepressive disorderdietmicrobiotamood disordersnutrientsprobiotics

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Area of Science:

  • Nutritional Psychiatry
  • Neuropsychiatric Disorders
  • Mood Disorders

Background:

  • Nutritional psychiatry is an emerging field exploring diet's role in mental health.
  • Factors like obesity, diet patterns, gut microbiome, and nutrients influence mood disorder pathophysiology.
  • The gut-brain axis plays a critical role in the nutrition-mood interaction.

Purpose of the Study:

  • To review current evidence on nutrition-mood interactions.
  • To examine nutrition-based treatments for major depressive disorder and bipolar disorder.
  • To highlight the role of the gut-brain axis in mood disorders.

Main Methods:

  • Review of observational studies and clinical trials on diet and mood disorders.
  • Analysis of the impact of dietary patterns (healthy vs. Western) on mood disorder risk.
  • Exploration of the gut-brain axis and its modulation through nutrition.

Main Results:

  • Observational studies link healthy diets to decreased mood disorder risk and Western diets to increased risk.
  • Limited clinical trials exist for nutritional interventions in mood disorder treatment.
  • The gut-brain axis is central to the relationship between nutrition and mood.

Conclusions:

  • Dietary patterns significantly influence the risk and potentially the treatment of mood disorders.
  • Nutritional interventions, particularly those modulating the gut microbiome, are promising for mood disorders.
  • Further clinical research is needed to establish evidence-based nutritional treatments.