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Multiple Xanthogranulomas in an Adult Patient with Myelodysplastic Syndrome
Marta Martínez-García1, Nicolás Silvestre-Torner1, Antonio Aguilar-Martínez1
1Dermatology Service, Severo Ochoa University Hospital, Leganés, Madrid, Spain.
Adult multiple xanthogranuloma (XG) is a rare condition presenting as skin nodules. This case highlights XG as a potential skin marker for blood disorders like myelodysplastic syndrome.
Area of Science:
- Dermatology
- Hematology
- Pathology
Background:
- Adult multiple xanthogranuloma (XG) is a rare, late-onset variant of juvenile XG.
- It typically manifests as papules or nodules, predominantly on the trunk.
Observation:
- Presents a case of a 54-year-old man with myelodysplastic syndrome.
- The patient exhibited multiple brownish papules primarily on his trunk.
Findings:
- Only 22 cases of adult XG have been reported, with 9 linked to hematological malignancies.
- This case adds to the limited literature on adult XG.
Implications:
- Adult XG may serve as a significant cutaneous marker for underlying blood dyscrasias.
- Early recognition of adult XG could prompt investigation for hematological disorders.
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