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Updated: Nov 20, 2025

Syntheses, Crystallization, and Spectroscopic Characterization of 3,5-Lutidine N-Oxide Dehydrate
Published on: April 24, 2018
Mono-N-oxidation of heterocycle-fused pyrimidines
Yongxing Tang1, Kejia Li, Ajay Kumar Chinnam
1Nanjing University of Science and Technology, Nanjing, 210094, China. yongxing@njust.edu.cn.
Abstract:
Three nitrogen-rich heterocyclic compounds containing the diamino-pyrimidine mono-N-oxide moiety were synthesized via mild oxidation reactions. Oxidation of the furazano-pyrimidine compound (1) with a mixture of trifluoroacetic anhydride (TFAA) and hydrogen peroxide (50%) gave the nitrate salt (3). All of the compounds were characterized by NMR spectra, elemental analysis, and single-crystal X-ray diffraction. They show high thermal stability and good detonation performance as well as low sensitivity.
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