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Updated: Nov 20, 2025

An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat
Published on: May 19, 2020
Mitral endocarditis in hypertrophic obstructive cardiomyopathy with leaflet perforation.
Hiroko Taguchi1, Shun Nakaji2, Yuichi Tasaki2
1Department of Cardiovascular Surgery, Nagasaki University Hospital, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan. hiroko3119@gmail.com.
This study details a case of mitral endocarditis in hypertrophic obstructive cardiomyopathy. Surgical repair of the perforated mitral valve and septal myectomy effectively managed the condition.
Area of Science:
- Cardiology
- Cardiac Surgery
- Infective Endocarditis
Background:
- Hypertrophic obstructive cardiomyopathy (HOCM) is a genetic heart muscle disease.
- Systolic anterior motion (SAM) of the mitral valve is a common complication in HOCM.
- Mitral endocarditis is a serious infection affecting heart valves.
Observation:
- A patient presented with mitral endocarditis superimposed on HOCM with significant SAM.
- The anterior mitral leaflet was perforated, leading to mitral regurgitation.
Findings:
- Surgical intervention included repair of the perforated anterior mitral leaflet.
- An extended septal myectomy was performed concurrently to address the obstruction and SAM.
- The combined procedure successfully controlled mitral regurgitation and HOCM symptoms.
Implications:
- This case highlights a successful combined surgical approach for complex HOCM with endocarditis.
- Effective management of mitral valve pathology is crucial in HOCM patients.
- Surgical strategies can be tailored to address both obstructive physiology and infectious complications.
Related Concept Videos
Mitral Stenosis I: Introduction
Mitral Valve Prolapse I: Introduction
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Mitral Regurgitation I: Introduction
Mitral Stenosis III: Medical Management
Mitral Stenosis II: Clinical features and Diagnostic Tests

