Hypertensive hypertrophic obstructive cardiomyopathy crisis resolved with transvenous pacing guided by bedside
Jeffrey F Spindel1, Mohammad Mathbout2, Shahab Ghafghazi2
1Department of Internal Medicine, University of Louisville, Louisville, KY, USA.
Insights
Cardiogenic shock in hypertensive hypertrophic obstructive cardiomyopathy (HHoCM) is challenging. Transvenous pacing optimized hemodynamics in an elderly woman with HHoCM and severe mitral regurgitation.
Area of Science:
- Cardiology
- Cardiovascular Medicine
Background:
- Cardiogenic shock from hypertrophic obstructive cardiomyopathy (HoCM) poses treatment challenges.
- Pharmacologic agents can worsen hemodynamics or left ventricular outflow tract (LVOT) obstruction.
- Hypertensive hypertrophic obstructive cardiomyopathy (HHoCM) in elderly women can mimic HoCM crisis.
Observation:
- An 81-year-old female patient presented with cardiogenic shock.
- The patient had hypertensive hypertrophic obstructive cardiomyopathy (HHoCM) with severe mitral regurgitation.
- Hemodynamic instability was the primary clinical concern.
Findings:
- Transvenous pacing was employed as a therapeutic strategy.
- Bedside echocardiography guided pacing to optimize heart rate and LV filling.
- This approach successfully restored hemodynamic stability.
Implications:
- Transvenous pacing offers a potential alternative for managing cardiogenic shock in HHoCM.
- Optimizing rate and LV filling time is crucial for hemodynamic support.
- This case highlights a novel approach for a complex cardiovascular condition.
Abstract:
Cardiogenic shock due to hypertrophic obstructive cardiomyopathy (HoCM) crisis presents a clinical challenge as pharmacologic vasopressor and/or inotropic support can compromise hemodynamics and acute afterload reduction worsens left ventricular outflow tract (LVOT) obstruction. Hypertensive hypertrophic obstructive cardiomyopathy (HHoCM) is an entity mostly affecting elderly hypertensive women and could present with a clinical phenotype similar to HoCM crisis. We present a case of an 81-year-old female patient with HHoCM complicated by severe mitral regurgitation, in cardiogenic shock, in whom hemodynamic stability was restored with transvenous pacing guided by bedside echocardiography to optimize rate, left ventricle (LV) filling time, and cardiac output.
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