Related Experiment Video

Updated: Aug 14, 2026

Multimodality Diagnosis of Mesenteric Ischemia
05:07

Multimodality Diagnosis of Mesenteric Ischemia

Published on: July 21, 2023

Venous mesenteric infarction: a particular entity

P A Clavien1, M Dürig, F Harder

  • 1Department of Surgery, University Hospital, Basle, Switzerland.

The British Journal of Surgery
|March 1, 1988
PubMed

Insights

Mesenteric venous thrombosis (MVT) presents with longer pain duration and localized bowel ischemia, leading to lower mortality than other causes. Early anticoagulation after wide resection is crucial for better survival.

Area of Science:

  • Gastroenterology
  • Vascular Surgery
  • Pathology

Background:

  • Mesenteric infarction is a critical condition with high mortality.
  • Mesenteric venous thrombosis (MVT) is a less common cause of mesenteric infarction.
  • Understanding MVT's distinct characteristics is vital for improved patient outcomes.

Purpose of the Study:

  • To differentiate clinical features, surgical findings, and outcomes of mesenteric venous thrombosis (MVT) from other causes of mesenteric infarction.
  • To evaluate the in-hospital mortality and survival rates for patients with MVT.
  • To establish optimal management strategies for MVT to reduce recurrence.

Main Methods:

  • Retrospective review of 98 patients with documented mesenteric infarction over 19 years.
  • Analysis of clinical presentation, surgical findings, and patient outcomes, specifically comparing MVT cases (13 patients) with other etiologies (85 patients).
  • Statistical comparison of pain duration, extent of bowel ischemia, operability, mortality, and survival rates.

Main Results:

  • MVT patients exhibited a significantly longer history of pain (median 8 days) before admission.
  • Surgical findings in MVT cases included typical bowel appearance and localized ischemia (<120 cm), facilitating operability.
  • In-hospital mortality was substantially lower for MVT (38%) compared to other causes (82%).
  • Primary MVT patients had better survival rates than those with associated conditions like liver cirrhosis or sepsis.
  • High recurrence rates were linked to residual thrombosis and hypercoagulable states.

Conclusions:

  • Mesenteric venous thrombosis (MVT) is characterized by distinct clinical and surgical features and is associated with significantly lower mortality.
  • Wide bowel resection followed by early and long-term anticoagulation is recommended for MVT management.
  • Thrombectomy is likely inefficient due to incomplete thrombus removal, potentially leading to recurrence.

More Related Videos

Controlled Reversible Visceral Arterial Ischemia, Venous Congestion and Combined Malperfusion via Midline Laparotomy in Rats04:57

Controlled Reversible Visceral Arterial Ischemia, Venous Congestion and Combined Malperfusion via Midline Laparotomy in Rats

Published on: July 5, 2024

Visualization of Neutrophil Extracellular Traps in Mesenteric Venules After Mesenteric Ischemia-Reperfusion Injury via Intravital Microscopy07:05

Visualization of Neutrophil Extracellular Traps in Mesenteric Venules After Mesenteric Ischemia-Reperfusion Injury via Intravital Microscopy

Published on: September 27, 2024

Related Concept Videos

Esophageal Varices-I: Introduction01:24

Esophageal Varices-I: Introduction

Esophageal varices are dilated, tortuous veins which are found mainly in the submucosa of the lower esophagus but which may also appear higher up or extend into the stomach. They develop due to increased pressure in the portal venous system, often as a result of liver cirrhosis. This condition scars and damages the liver, impeding normal blood flow through the portal vein. To compensate, blood seeks alternative pathways, forming fragile new vessels (varices) in the esophagus and stomach. These...
Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
Ischemic Stroke l: Introduction01:15

Ischemic Stroke l: Introduction

Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
Ischemic Stroke ll: Pathophysiology01:15

Ischemic Stroke ll: Pathophysiology

An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
Transient Ischemic Attack l: Introduction01:26

Transient Ischemic Attack l: Introduction

A transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by a temporary, focal reduction in cerebral blood flow. Although symptoms resemble those of an ischemic stroke, the interruption in perfusion is short-lived and does not cause permanent infarction. TIAs are clinically important because they often serve as early warning events for future stroke.Mechanisms of Transient Cerebral IschemiaTransient cerebral ischemia may arise through several mechanisms. One...