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Related Experiment Videos

Venous mesenteric infarction: a particular entity.

P A Clavien1, M Dürig, F Harder

  • 1Department of Surgery, University Hospital, Basle, Switzerland.

The British Journal of Surgery
|March 1, 1988
PubMed
Summary
This summary is machine-generated.

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Mesenteric venous thrombosis (MVT) presents with longer pain duration and localized bowel ischemia, leading to lower mortality than other causes. Early anticoagulation after wide resection is crucial for better survival.

Area of Science:

  • Gastroenterology
  • Vascular Surgery
  • Pathology

Background:

  • Mesenteric infarction is a critical condition with high mortality.
  • Mesenteric venous thrombosis (MVT) is a less common cause of mesenteric infarction.
  • Understanding MVT's distinct characteristics is vital for improved patient outcomes.

Purpose of the Study:

  • To differentiate clinical features, surgical findings, and outcomes of mesenteric venous thrombosis (MVT) from other causes of mesenteric infarction.
  • To evaluate the in-hospital mortality and survival rates for patients with MVT.
  • To establish optimal management strategies for MVT to reduce recurrence.

Main Methods:

  • Retrospective review of 98 patients with documented mesenteric infarction over 19 years.

Related Experiment Videos

  • Analysis of clinical presentation, surgical findings, and patient outcomes, specifically comparing MVT cases (13 patients) with other etiologies (85 patients).
  • Statistical comparison of pain duration, extent of bowel ischemia, operability, mortality, and survival rates.

    • Main Results:

    • MVT patients exhibited a significantly longer history of pain (median 8 days) before admission.
    • Surgical findings in MVT cases included typical bowel appearance and localized ischemia (<120 cm), facilitating operability.
    • In-hospital mortality was substantially lower for MVT (38%) compared to other causes (82%).
    • Primary MVT patients had better survival rates than those with associated conditions like liver cirrhosis or sepsis.
    • High recurrence rates were linked to residual thrombosis and hypercoagulable states.

    Conclusions:

    • Mesenteric venous thrombosis (MVT) is characterized by distinct clinical and surgical features and is associated with significantly lower mortality.
    • Wide bowel resection followed by early and long-term anticoagulation is recommended for MVT management.
    • Thrombectomy is likely inefficient due to incomplete thrombus removal, potentially leading to recurrence.