Risk Factors of Intervertebral Disc Pathology-A Point of View Formerly and Today-A Review

Intervertebral disc pathology is a common disorder that can be caused by genetic, mechanical, and behavioral factors; however, it is possible to slow its progression. Although environmental and behavioral factors were previously considered to be the sole causes of intervertebral disc pathologies such as disc herniation, recent studies have shown that genetic factors also play an important role. This review compares the perception of major risk factors from the last and present centuries. It also examines individual genetic and non-genetic factors acting as risk factors, as well as some approaches for preventing intervertebral disc pathologies, and compares available statistics regarding disc herniation.